DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
Diatoms are single celled eukaryotic microalgae that self-assemble complex SiO₂
nanostructures by sillafin proteins within their cell wall. There has been increasing
interest in mimicking the diatom’s silica self-assembly process for fabricating metal
oxide nanoparticles, namely germanium dioxide (GeO₂). GeO₂ has a higher refractive
index than silica, enabling it to...
China’s global influence in the realm of science and technology (S&T) has increased dramatically in recent times. China and the United States are now each other’s main partner in scientific collaboration. As a major research university, OSU is one of the institutions with a large stake in this international collaboration....
Landfill leachate is a complex wastewater that contains high levels of ammonium (often over 250 ppm) and trace heavy metals (usually under 0.2 ppm). Microalgae have been shown to inexpensively and effectively treat wastewaters containing high loads of organics and nutrients, as well as adsorb metal ions. This thesis focuses...
Since the 1960s, Vietnamese scholars have written autobiographical literature catered to the American public though they have not gotten as much recognition as soldier accounts and anti-war literature. These Vietnamese literatures shifted in scope and form with the succeeding waves of refugee resulted from the war in Việt Nam. As...
A rapidly expanding body of evidence suggests that relationships exist between the microbiome and vertebrate health and disease. The zebrafish is a frequently utilized model organism to support this claim. Specifically, its gut microbiome is an advantageous resource for the study of microbiome health and diversity. While it is an...
Objective: To perform a systematic review and meta-analysis on the prevalence rate of mental health disorders including anxiety, depression, and insomnia during the COVID-19 pandemic in Eastern Europe in the general population, as well as within select sub-populations (i.e., students, general healthcare workers, and frontline workers).
Data sources: Articles in PubMed,...
Rice (Oryza sativa) is a common crop found in various regions worldwide where it is considered a staple food. Though widespread, O. sativa plants' growth, development, and yield are affected by environmental/abiotic stresses including drought, salinity, flooding, cold, heat, etc. Particularly, salinity stress leads to dehydration, overwhelms potassium pumps, and...
The Polycomb Repressive Complex 2 (PRC2) catalyzes genome transcription repression through the methylation of lysine residue 27 in the amino terminal region of histone 3 (H3K27me1/2/3) [2], [7]. PRC2 is made up of three highly conserved core subunits: Kmt6, Eed, and Suz12. Accurate distribution of PRC2 is essential for proper...