Age-related decline in the capacity of endogenous antioxidant systems
complicates pharmaceutical use by the elderly by potentially increasing the toxicity of
some compounds. Of particular interest is chemical detoxification via glutathione (GSH)
and attendant GSH-requiring detoxification enzymes, e.g. GSH peroxidases (GPX) and
GSH S-transferase (GST). These enzymes have been shown...
Instance segmentation, the classification and localization of objects in an image, is a problem in cellular biophysics due to the physiological relevance of cell morphology. Particularly, cancer cells migrate in tissue space by changing their body shape similarly to how humans extend their limbs to swim through water. Monitoring such...
The main goal of this project is to implement an algorithmic music composition procedure and present all procedures and results in a reproducible fashion by creating a web application produced by R. To approach the implementation of the algorithmic composition of music, we start by exploring various models, but ultimately...
Gene expression is largely regulated by the binding of transcription factors to short sequences of DNA (transcription factor binding sites) to drive or repress transcription of an adjacent gene. Identifying the key transcription factor binding sites associated with a particular biological outcome provides an avenue for tailored transcriptional regulation in...
The opioid epidemic in the U.S. has had significant impacts on opioid overdose rates, productivity, and healthcare expenditure. Research has drawn attention to the necessity of a more integrated, biopsychosocial approach to treatment of chronic pain, and how it could alleviate the current public health emergency. Previous literature alluded to...
Understanding the electrical transport properties of graphene provides a basis for determining its future as a potential semiconducting device that can be used for the next generation of transistors and photodetectors. Graphene p-n junctions can also function as field effect transistors, and thus are a logical starting point for I-V...
The Pacific Walrus population that lives within the Chukchi Sea near Alaska and the Russian territory Siberia have traditionally held a diet composed of molluscs and benthic invertebrates, with the main dietary choice being clams or other bivalves. Due to global warming, the availability of stable ice resting surfaces has...
In this piece of original work, I employ a Kunderian approach to fiction. The purpose of my novel is to examine how the causative element, a pivotal moment of change for a cast of characters, changes spatially and temporally. In Posthumously Yours, I explore themes of trauma, loss, and grief...