Uveitis is a serious ophthalmological disorder characterized by intraocular infiltration of inflammatory cells. In most cases, uveitis is derived from the adaptive immune response. More specifically, CD4+ T lymphocytes play an important role in the pathogenesis of uveitis by recognizing uveitogenic antigen and orchestrating the immune response. While it is...
In recent decades, the occurrence of large, high severity wildfires has increased substantially in many parts of the world, including the western United States. These fires have the potential to impact water quality, aquatic ecosystems, and downstream communities for many decades. As such, it is increasingly important to understand the...
The Central American Free Trade Agreement (CAFTA) is between the United States and Costa Rica, Nicaragua, Honduras, Guatemala, El Salvador and the Dominican Republic. CAFTA was decided in Costa Rica by a national referendum in 2007, after years of delay that left Costa Rica as the only country to have...
Information about social and economic attributes of fisheries, fishing communities, and fishery participants is important for marine resource management because the focuses of agency efforts are on managing society's impacts to the marine environment. This thesis addresses two questions. First, what are the perspectives of managers, scientists, and commercial and...
Studies have established that there is a greater risk for onset of adult metabolic syndrome disease such as diabetes mellitus, hypertension, hyperlipidemia, and obesity in subjects born with low birth weight (LBW). Undernourished fetuses make adaptions that result in structurally, morphologically, and functionally altered organs. In terms of drug pharmacokinetics,...
The rise of digital streaming has largely impacted the way the average listener consumes music. Consequentially, while the role of album art has evolved to meet the changes in music technology, it is hard to measure the effect of digital streaming on modern album art. This research seeks to determine...
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Andrea Marks, Committee Member, representing the School of Marketing, Analytics and
Design
Background: Lateral gene transfer (LGT) among C. trachomatis strains is common, both in isolates generated in the laboratory and those examined directly from patients. This is a challenging concept because there are very few examples of recent acquisition of foreign DNA by Chlamydia spp. There is no understanding of the...
Today, with countless study abroad programs available, students have the opportunity to travel and study all over the world. Those who are lucky enough to study abroad are able to embark on an international journey that will change their life forever. This thesis expands on what happens after returning home...
The experiments explained in this Honors thesis are focused on finding a cellular model for analyzing Bcl11b, a transcription factor dysregulated in 20% of cases of T-cell Acute Lymphoblastic Leukemia (T-ALL). Acute Lymphoblastic Leukemia is the most common childhood cancer. Because T-ALL is a result of incorrect thymocyte development, research...