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Gender-Dependent Mechanisms of Alpha-Tocopherol Protection from Benzo[a]pyrene Exposure in Rats

Creator:: Crimp, Caitlin A.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (B[a]P), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (αT) supplementation decreases B[a]P-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that αT protection from B[a]P exposure is gender-dependent, male and female rats received 7 daily subcutaneous...
Resource Type:: Honors College Thesis
Full Text:: : Debbie Mustacich Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (B[a]P), are

Adjuvant vitamin E and ovarian cancer

Creator:: Hartman, Alysha E.
Abstract:: Cisplatin (CDDP) is a highly active platinum-containing chemotherapeutic agent for use against solid tumors, including ovarian. However, like most antitumor agents, CDDP use is accompanied by non-tumor tissue toxicities leading to unwanted side effects, including neuropathy. To date, the mechanism(s) for these side effects are undefined. However, the clinical features...
Resource Type:: Presentation

Gender-Dependent Mechanisms of Alpha-Tocopherol Protection from Benzo[a]pyrene Exposure in Rats

Creator:: Crimp, Caitlin A. and Mustacich, Debbie J.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (BP), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (aT) supplementation decreases BP-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that aT protection from BP exposure is gender-dependent, male and female rats received 7 daily subcutaneous...
Resource Type:: Poster
Full Text:: Thesis of Caitlin A. Crimp Mentor: Debbie J. Mustacich, Ph.D. Polycyclic aromatic hydrocarbons (PAHs

Chromosomal Recombination Targets in Chlamydial Lateral Gene Transfer In Vitro

Creator:: Kim, Debbie Blue
Abstract:: Background: Lateral gene transfer (LGT) among C. trachomatis strains is common, both in isolates generated in the laboratory and those examined directly from patients. This is a challenging concept because there are very few examples of recent acquisition of foreign DNA by Chlamydia spp. There is no understanding of the...
Resource Type:: Honors College Thesis
Full Text:: Chromosomal Recombination Targets in Chlamydial Lateral Gene Transfer In Vitro by Debbie Blue Kim

Speaking about Women in the Year of Hillary Clinton

Creator:: Hagen-Young, Meshayla
Abstract:: PS 300 -
Resource Type:: Research Paper
Full Text:: families, specifically women: “…Congresswomen Debbie Dingell (MI-12) joined with Michigan legislators

Kinetics of plankton respiration across gradient of anoxic to oxic conditions

Creator:: Jayawickrama, Clare
Abstract:: Ocean deoxygenation is predicted to increase in severity over the next few decades, posing a threat to marine life and fishing economies. Improved predictions of ocean deoxygenation depend on a better understanding of the biogeochemical mechanisms that underly this process. Within the realm of biogeochemical mechanisms, this project specifically investigated...
Resource Type:: Honors College Thesis
Full Text:: Barnard, A. H., B. Rhoades, C. Wetzel, A. Derr, J. R. V. Zaneveld, C. Moore, C. Koch, and I. Walsh

Studies Toward the Synthesis of Natural Product Scaffolds

Creator:: Lusk, Jason S.
Abstract:: Part 1: A Diels-Alder Approach to the Synthesis of Novel Analogues of the Natural Product Siamenol Due to the prevalence of biaryl motifs in natural product synthesis, the Carter research group has been exploring the utility of a Diels-Alder approach to biaryl synthesis. The Diels-Alder approach involves a [4+2] cycloaddition...
Resource Type:: Honors College Thesis
Full Text:: This thesis is dedicated to my wonderful parents, Scott and Debbie Lusk. Thank you for your

Exploring the functional effects of Leukemia-promoting natural mutations in the tumor suppressor protein, BCL11B

Creator:: Wisner, Heather
Abstract:: Thymocytes, cells of the thymus gland, undergo developmental steps that enable them to properly mature into T-cells. Errors in gene expression may lead to improper maturation and potentially mass proliferation of dysfunctional thymocytes, a hallmark of leukemia or lymphoma. BCL11B is a tumor suppressor and transcriptional regulatory protein that is...
Resource Type:: Honors College Thesis
Full Text:: Debbie Wisner for their constant encouragement. TABLE OF CONTENTS Page Introduction

Mismatch Repair-Dependent Cellular Responses to Polycyclic Aromatic Hydrocarbons: An Investigation of Research Methods and Materials

Creator:: Wickramanayake, Anneka
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic chemical compounds found in the environment, largely as a result of partial combustion of organic compounds. PAHs are present in the atmosphere in populated cities worldwide. Because of the health risks they create, PAHs are a global health concern. PAHs are introduced into the...
Resource Type:: Honors College Thesis

Do Slasher Films Breed Violence Against Women?

Creator:: Kimsey, Jennfer M.
Abstract:: A topic of concern for feminists, film critics, media researchers, and film scholars alike who believe in a causal connection between film violence and real life violence have found an enemy in the slasher film. Critics of slasher films, a subgenre of horror, often charge these films are uniquely violent...
Resource Type:: Honors College Thesis
Full Text:: ). Psycho ~--:--'-;, _. W~'''-~'J~~~l"~.:J_.... ,..~---_"""'''''0'''~:''_~'~ _.P'""~ DO SLASHER FILMS

ScholarsArchive@OSU

Gender-Dependent Mechanisms of Alpha-Tocopherol Protection from Benzo[a]pyrene Exposure in Rats

Adjuvant vitamin E and ovarian cancer

Gender-Dependent Mechanisms of Alpha-Tocopherol Protection from Benzo[a]pyrene Exposure in Rats

Chromosomal Recombination Targets in Chlamydial Lateral Gene Transfer In Vitro

Speaking about Women in the Year of Hillary Clinton

Kinetics of plankton respiration across gradient of anoxic to oxic conditions

Studies Toward the Synthesis of Natural Product Scaffolds

Exploring the functional effects of Leukemia-promoting natural mutations in the tumor suppressor protein, BCL11B

Mismatch Repair-Dependent Cellular Responses to Polycyclic Aromatic Hydrocarbons: An Investigation of Research Methods and Materials

Do Slasher Films Breed Violence Against Women?

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