Index Catalog // ScholarsArchive@OSU

Classification and Analysis of Nucleotide - Nucleotide Interactions in RNA

Creator:: Rouches, Mason
Abstract:: Base-pairing interaction are the fundamental blocks of an RNA structure. With increased ability to determine the structure of RNA molecules, an accurate and informative way of classifying these interactions would help to study RNA structure at many levels. Apart from the well-known complementary base pairs and wobble pairs, other interactions...
Resource Type:: Honors College Thesis
Full Text:: - Nucleotide Interactions in RNA by Mason Rouches A THESIS

The Role of Arabidopsis RNA-Dependent RNA Polymerase Genes 3, 4 and 5 in Antiviral Defense

Creator:: Lowery, Nicholas C.
Abstract:: RNA silencing plays a critical role in plant defense against viral infection. Plants use virusderived small interfering RNA to target and silence invading viruses. The antiviral silencing pathway can be broken down into three conceptual stages: initiation, amplification, and systemic movement. The molecular mechanisms of silencing initiation are not well...
Resource Type:: Honors College Thesis
Full Text:: . Title: The Role of Arabidopsis RNA-Dependent RNA Polymerase Genes 3, 4 and 5 in Antiviral Defense

Vegetative effects of RNAi-suppression of the poplar homolog of LEAFY in the field

Creator:: Jacobson, Jeremy
Abstract:: Due to public and regulatory restrictions, genetic containment technology is critical for research and development of transgenic trees in forestry. A multi-year field trial demonstrated that the RNAi-LFY construct successfully induces sexual sterility in 6K10 poplar (Populus alba) without visible effects on vegetative development. However, its limited number of replicates...
Resource Type:: Undergraduate Thesis and Presentation
Full Text:: meristem to the floral meristem LFY 13 Floral MeristemInflorescence Meristem RNA interference (RNAi

Comparison of Canine Spermatozoa Motility, Morphology, and RNA Integrity Using Three Different Cell Purification Solutions

Creator:: Hegedus, Rachel M.
Abstract:: Transcriptome gene expression studies of sperm RNA have been utilized in a variety of different species to investigate causes of male infertility. Previous research investigators have optimized cell separation and RNA isolation techniques for each species of interest. To date, no study has been completed for dogs. The objective of...
Resource Type:: Honors College Thesis
Full Text:: , 2014. Title: Comparison of Canine Spermatozoa Motility, Morphology, and RNA Integrity Using Three

Investigating Local Energy Compensation of Adjacent RNA Secondary Structures in the bpRNA-1m Database

Creator:: Cornwell-Arquitt, Robert L.
Abstract:: Non-coding ribonucleic acid (ncRNA) is of interest for its diverse roles in cell and viral biology. RNA molecules vary greatly in terms of size, structure, and function. In recent years, the modification of existing RNA structures has been used for biochemical methods of enormous impact including CRISPR and RNAi methods....
Resource Type:: Honors College Thesis
Full Text:: Investigating Local Energy Compensation of Adjacent RNA Secondary Structures in the bpRNA-1m Database

De novo Discovery of Novel Long Noncoding RNAs in the North American Beaver

Creator:: Kashyap, Amita
Abstract:: Long noncoding RNAs (lncRNAs) are RNA molecules that are at least 200 nucleotides long and do not encode proteins. lncRNAs have roles in gene regulation, chromatin epigenetics, and molecular scaffolding. In light of mounting evidence implicating species-specific noncoding RNAs and gene regulatory mechanisms in species adaptations, it is reasonable to...
Resource Type:: Honors College Thesis
Full Text:: PowerPoint Presentation Long Noncoding RNA in the North

Sulforaphane Regulation of LncRNA in a Transplacental Nrf2 Knockout Mouse Model Exposed to Dibenzo[def,p]chrysene

Creator:: Patel, Karan A.
Abstract:: Dibenzo[def,p]chrysene (DBC) is a highly potent, but less prevalent, environmental carcinogen belonging to a class of compounds known as Polycyclic Aromatic Hydrocarbons (PAHs). They are highly ubiquitous and arise as a byproduct of natural and anthropogenic combustion processes. Previous studies have documented carcinogenic effects upon in utero exposure of PAHs....
Resource Type:: Honors College Thesis
Full Text:: of various long non-coding RNA (lncRNA >200bp) utilizing a Nrf2 Knockout Mouse Model. LncRNA have

Method development for extraction and purification of dermal RNA from FVB/Nmice treated with environmental PAH mixtures

Creator:: Larkin, Andrew, Siddens, Lisbeth, and Krueger, Sharon
Abstract:: Epidermal RNA samples from FVB/N mice treated with PAH standards and environmental PAH mixtures were harvested and purified using Trizol extraction and RNeasy mini prep kit purification. Epidermal RNA integrity was low (RIN mean 3.5), indicating significant RNA degradation and the need to modify handling, collection, and processing of skin...
Resource Type:: Undergraduate Thesis and Presentation

Characterization of the SARS-CoV-2 Nucleocapsid Protein and the Binding to Different Sections of the SARS-CoV-2 Genome

Creator:: Pinckney, Seth H.
Abstract:: The nucleocapsid protein (N protein) of the severe acute respiratory syndrome coronavirus 2 is known to play an essential part of the virus’ functions. The N protein can protect and package the large 29,903 nucleotide genomic RNA whilst also interacting with structural membrane protein M and the spike protein S....
Resource Type:: Honors College Thesis
Full Text:: genomic RNA whilst also interacting with structural membrane protein M and the spike protein S. The full

Liquid-liquid Phase Separation of the Nucleocapsid of SARS-CoV-2

Creator:: Hughes, Kaitlyn
Abstract:: The nucleocapsid of SARS-CoV-2 is critical for viral genome packaging through binding to viral genomic RNA. Liquid-liquid phase separation, or LLPS, is the formation of microscopic, rapidly reversible, liquid-like immiscible droplets. There is increasing scientific evidence that LLPS underlies the formation of membraneless compartments within cells and that this process...
Resource Type:: Honors College Thesis
Full Text:: binding to viral genomic RNA. Liquid-liquid phase separation, or LLPS, is the formation of microscopic

ScholarsArchive@OSU

Classification and Analysis of Nucleotide - Nucleotide Interactions in RNA

The Role of Arabidopsis RNA-Dependent RNA Polymerase Genes 3, 4 and 5 in Antiviral Defense

Vegetative effects of RNAi-suppression of the poplar homolog of LEAFY in the field

Comparison of Canine Spermatozoa Motility, Morphology, and RNA Integrity Using Three Different Cell Purification Solutions

Investigating Local Energy Compensation of Adjacent RNA Secondary Structures in the bpRNA-1m Database

De novo Discovery of Novel Long Noncoding RNAs in the North American Beaver

Sulforaphane Regulation of LncRNA in a Transplacental Nrf2 Knockout Mouse Model Exposed to Dibenzo[def,p]chrysene

Method development for extraction and purification of dermal RNA from FVB/Nmice treated with environmental PAH mixtures

Characterization of the SARS-CoV-2 Nucleocapsid Protein and the Binding to Different Sections of the SARS-CoV-2 Genome

Liquid-liquid Phase Separation of the Nucleocapsid of SARS-CoV-2

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