An emerging strategy to reducing food waste is converting food processing byproducts to nutritious and inexpensive food ingredients. A relevant food processing waste stream is brewers’ spent grain (BSG), the primary byproduct of beer production. BSG is a promising candidate as a food ingredient because of its high protein and...
The Ambovombe-Androy region of southern Madagascar is one of the most water stressed areas in the country and is also notorious for having the worst quality water on the island. Before improvements and change can be made however, it is vital to know what infrastructure, quality, and access levels currently...
The Polycomb Repressive Complex 2 (PRC2) catalyzes genome transcription repression through the methylation of lysine residue 27 in the amino terminal region of histone 3 (H3K27me1/2/3) [2], [7]. PRC2 is made up of three highly conserved core subunits: Kmt6, Eed, and Suz12. Accurate distribution of PRC2 is essential for proper...
"‘Biometrics is at the forefront in our agenda for homeland security,’ declared Asa Hutchinson, the Department of Homeland Security's undersecretary for border and transportation security, at the 2004 Biometric Consortium Conference” [11].
Flashy retinal scanning and voice activated computers were once considered technologies for science fiction movies and novels. Nowadays,...
Histones, as part of nucleosomes, are responsible for DNA packaging in chromosomes. They also affect DNA expression by a multitude of post-translational modifications, especially prevalent on the amino terminus of histones. Co-activator protein complexes “write”, “read”, or “erase” histone modifications, and in balance determine which sections of DNA are free...
PRC2 (Polycomb Repressive Complex 2) mediated gene silencing plays an important role in cell differentiation, stem cell plasticity, and tumor suppression. In fungi, it is also involved in pathogenicity. The catalytic subunit, KMT6, trimethylates lysine 27 on histone h3 (H3K27me3) at loci targeted for silencing. In animals, PRC1 and PRC2...
Biomass pretreatment-derived degradation compounds, such as furfural and 5-hydroxymethyl-furfural (HMF),inhibit the growth of fermentation microorganisms that utilize biomass to produce biofuels and chemicals. Here we report that manganese(III) can degrade furfural and HMF, making them less toxic to microorganisms. Treatment with manganese(III) reduced furfural and HMF concentrations in a dose-dependent...
Polycomb Repressive Complex 2 (PRC2) is a histone methyltransferase that initiates facultative heterochromatin formation by trimethylating histone H3 on lysine 27 (H3K27me3). Mutations within its three primary subunits, KMT6, EED, and SUZ12, result in inherited diseases and sporadic cancers. In the fungus Fusarium graminearum, deletion of the gene encoding the...
Modifications of histone tail amino acid residues are necessary for many reactions involving chromatin. These processes can produce transcriptionally active, euchromatic, or inactive, heterochromatic, segments of DNA. The formation and maintenance of facultative heterochromatin is critical for the proper growth and development of many eukaryotes. Euchromatin can be changed into...