Cisplatin (CDDP) is a highly active platinum-containing chemotherapeutic agent for use against solid tumors, including ovarian. However, like most antitumor agents, CDDP use is accompanied by non-tumor tissue toxicities leading to unwanted side effects, including neuropathy. To date, the mechanism(s) for these side effects are undefined. However, the clinical features...
The Min protein system in Escherichia coli helps the cell division process by identifying the center of the cell [1, 7]. This system has been modeled succesfully computationally under standard conditions. There has been recent experimental interest in the cell division process for significantly perturbed cell shapes. We take the...
E+A galaxies represent an important niche in galaxy evolution as a subset of post-starburst galaxies. Set apart from other post-starburst galaxies by their rapid quenching of star formation, E+As are thought to have started their formation outside a galaxy cluster's center and have fallen inward due to gravity; the star...
Although assays have been done on the effects of vitamin E alpha-tocopherol (ɑ-tocopherol) on the lifespan of wildtype C. elegans, none have been done on the effects of the vitamin on mutant strains with mitochondrial mutations. By using a mev-1 genetic mutant strain of C. elegans with higher levels of...