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Filtering by: Creator Teng, Chung-chu Degree Level Bachelor's

Short-Term Lipid Overload in Skeletal Muscle Induces Mild Mitochondrial Membrane Depolarization as a Stimulus for Autophagy Activation

Creator:

Brinck, Isabel M.

Abstract:

Type 2 Diabetes Mellitus is a chronic metabolic condition that impairs insulin stimulated glucose absorption in skeletal muscle, a characteristic phenomenon denoted as insulin resistance. Lipid overload of the mitochondria is linked to the development of insulin resistance and the progression of Type 2 Diabetes. As lipids accumulate there is...

Resource Type:

Honors College Thesis

Full Text:

(Teng and Huang, 2019) due to its ability to absorb and metabolize approximately 80% of postprandial