Index Catalog // ScholarsArchive@OSU

Automethylation : a response to enzyme aging

Creator:: Lindquist, Jonathan A.
Abstract:: This is the first study to explore the ability of an enzyme to recognize and repair spontaneous age-dependent damage to its own sequence. Protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase (PCM) is known to repair damage that arises from a spontaneous isomerization of aspartyl and asparaginyl residues in other proteins during aging. As...
Resource Type:: Dissertation
Full Text:: . P. Shing Ho, Dr. Michael Schimerlik, and Dr. Carmen Somoza. And I would especially like to thank

DNA binding and beyond : an investigation of proteins involved in PAH-induced carcinogesesis

Creator:: Hooven, Louisa Ada
Abstract:: Exposure to polycyclic aromatic hydrocarbons such as benzo[a]pyrene (B[a]P) has been determined to be a risk factor for various forms of human cancer. PAH DNA adducts have been shown to cause mutations, but carcinogenesis is also accompanied by alterations in gene expression. Inhibiting individual cytochrome P450s could clarify the interaction...
Resource Type:: Dissertation
Full Text:: unwavering support. My appreciation is also extended to Dr. P. Shing Ho, Dr. Christopher K. Mathews, and Dr

Electron molecule interactions of amino acids and peptides

Creator:: Figard, Benjamin J.
Abstract:: Electron-biomolecule interactions are a biologically relevant field of study because there are several ion fragmentation techniques that have come to the forefront in mass spectrometric analysis that involve the interaction of charged peptides and free electrons. By studying the electron energies that cause fragmentation in neutral amino acids, amino acid...
Resource Type:: Dissertation
Full Text:: peptide substance P. For peptides with carboxylic acids on the C-terminus, z-1 ions were observed

Ligand binding to the muscarinic receptor : equilibrium and kinetic studies

Creator:: Hirschberg, Birgit T.
Resource Type:: Dissertation
Full Text:: . Robert for many helpful and encouraging discussions. Thanks to Drs. P. Shing Ho, Sonia R. Anderson, W

Hydrogenase in Azotobacter vinelandii : the role of the heme ligands in HoxZ

Creator:: Meek, Laura
Resource Type:: Dissertation
Full Text:: committee was particularly helpful to me and I would like to thank Chris Mathews, Kevin Gable, P. Shing Ho

Structural requirements for adenovirus DNA replication

Creator:: Hu, Chin-Hwa
Abstract:: The adenovirus replication origins reside in the inverted terminal repetition (ITR) sequences. Replication proceeds unidirectionally by a strand-displacement mechanism from either or both origins to produce duplex daughter DNA plus a displaced parental strand. The displaced strand can be duplicated by two different routes. The cis pathway involves intramolecular hybridization...
Resource Type:: Dissertation
Full Text:: . Pui Shing Ho, Dr. Dennis Hruby, and Dr. Peter Bottom ley, for their generous help. I also want to

Sequence conversion during adenovirus DNA replication

Creator:: Bennett, Kelly L.
Abstract:: The work in this thesis has provided conclusive genetic evidence that "panhandle" intermediates form during adenovirus replication. Adenovirus chromosomes lacking 51 by from their left -hand termini are infectious and capable of regenerating the missing origin sequence. Yet if an entire inverted terminal repeat is removed, the adenovirus chromosome is...
Resource Type:: Dissertation
Full Text:: extend my gratitude to my committee members, Dr. Christopher Mathews, Dr. Pui Shing Ho, Dr. Dal lice

Effects of nucleosomes on transcription by polymerase I in a reconstituted system

Creator:: Georgel, Philippe, 1961-
Abstract:: The aim of this study was to gain more information about the interactions between DNA and the histone octamer during the process of transcription. This work used a pUC8 plasmid derivative that contained the core promoter region of the RNA polymerase I of Acanthamoeba castellanii, placed upstream of four repeats...
Resource Type:: Dissertation
Full Text:: his support. All the members of my committee, professor Pui Shing Ho, professor Henry Schaup

Bacteriophage T4 ribonucleotide reductase : genes and proteins

Creator:: Hanson, Eric Scott
Resource Type:: Dissertation
Full Text:: . Lastly, I thank the members of my committee, Drs. Christopher Mathews, Douglas Barofsky, Shing Ho, Jo-Ann

Helical propensity of amino acids changes with solvent environment

Creator:: Krittanai, Chartchai
Resource Type:: Dissertation
Full Text:: committee members, Dr. Pui Shing Ho, Dr. Victor L. Hsu, Dr. Joseph W. Nib ler, and Dr. Carol J. Rivin for

ScholarsArchive@OSU

Automethylation : a response to enzyme aging

DNA binding and beyond : an investigation of proteins involved in PAH-induced carcinogesesis

Electron molecule interactions of amino acids and peptides

Ligand binding to the muscarinic receptor : equilibrium and kinetic studies

Hydrogenase in Azotobacter vinelandii : the role of the heme ligands in HoxZ

Structural requirements for adenovirus DNA replication

Sequence conversion during adenovirus DNA replication

Effects of nucleosomes on transcription by polymerase I in a reconstituted system

Bacteriophage T4 ribonucleotide reductase : genes and proteins

Helical propensity of amino acids changes with solvent environment

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