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Filtering by: Creator Maier, Claudia Degree Level Doctoral File Format application/pdf

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Creator:

Zhang, Yong

Abstract:

Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Prior research suggested that some isoforms of PLC-β may exist and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation assays of differentially-tagged PLC-β constructs and sizeexclusion chromatography of native PLC-β support homodimerization...

Resource Type:

Dissertation

Full Text:

. Paul Murtaugh, Dr. Claudia Maier and Dr. Lan Xue for their invaluable support and feedback during
Geneticist L.C. Dunn : politics, activism, and community

Creator:

Gormley, Melinda (Melinda Brooke)

Abstract:

L. C. Dunn (1893-1974) spent most of his scientific career conducting research in developmental genetics as a member of the Zoology Department at Columbia University in the City of New York. He had an accomplished scientific career researching mutations in mice, which earned him respect from other geneticists and scientists....

Resource Type:

Dissertation