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Filtering by: Creator Kleywegt, Gerard J. Remove constraint Creator: Kleywegt, Gerard J. Degree Level Doctoral Remove constraint Degree Level: Doctoral Language English [eng] Remove constraint Language: English [eng]

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  • Utilization of lignocellulosic polysaccharides

    Creator:
    Fenske, John J.
    Abstract:
    Lignocellulosic biomass represents a vast supply of fermentable carbohydrates and functional aromatic compounds. Conversion of lignocellulosics to ethanol and other useful products would be of widespread economical and environmental benefit. Better understanding of the behavior of different lignicellulosic feedstocks in fermentation protocols as well as catalytic activities involved in lignocellulosic...
    Resource Type:
    Dissertation
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    AN ABSTRACT OF THE THESIS OF John J. Fenske for the degree of

  • Quantification and reactivity of cellulose reducing ends : implication for cellulose

    Creator:
    Kongruang, Sasithorn
    Abstract:
    The primary purpose of this study was to (1) develop methods for the analysis of and (2) provide information on the chemical nature of reducing ends in typical cellulose substrates used for the study of cellulolytic enzymes. The studies were designed such that values obtained for cellulose substrates were compared...
    Resource Type:
    Dissertation
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    appreciation to Dr. Rosalyn Upson, Dr. John P. Bolte and Dr. John J. Garland as committee members. I am proud

  • Incorporating Uncertainty in Truckload Relay Network Design

    Creator:
    Mokhtari, Zahra
    Abstract:
    In a relay network for full truckload (TL) transportation, facilities known as relay points (RPs) serve as exchange points where truck drivers can exchange trailers. This would help carriers to assign more regular tours to drivers when compared to the excessively long tours that exist in the traditional Point-to-Point (PtP)...
    Resource Type:
    Dissertation
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    where a load is transported from node i to node j using three RPs. Figure 1: Example of a

  • Biophysical analyses of peroxiredoxins and a partner reductase

    Creator:
    Hall, Andrea Renée
    Abstract:
    Peroxiredoxins (Prxs) are dominant peroxide-reducing enzymes with two important roles: they protect all organisms from oxidative damage induced by peroxides, and in eukaryotes, they participate in hydrogen peroxide signaling pathways. This dissertation presents studies aimed at the biophysical characterization of select Prxs and a Prx reductase to elucidate their structure-function...
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    Dissertation
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    and hemoglobin, awarded to J. C. Kendrew, M. Perutz), there have been 16 Nobel Prizes in chemistry

  • Sequence dependent conformational variations in DNA holliday junctions

    Creator:
    Hays, Franklin A.
    Abstract:
    Four-stranded DNA junctions (also known as Holliday junctions) are structural intermediates involved in a growing number of biological processes including DNA repair, genetic recombination, and viral integration. Although previous studies have focused on understanding the conformational variability and sequence-dependent formation of Holliday junctions in solution there have been relatively few...
    Resource Type:
    Dissertation
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    role in the subsequent structure solution and refinement. Zebulon J. R. Jones provided some assistance

  • Operations Research Models for Blood Supply Chain Network Design for Disaster Planning

    Creator:
    Baik, Shefaa A.
    Abstract:
    A blood supply chain (BSC) deals with the collection, processing, storing, and distribution of blood collected from donors and delivered to patients at demand points (DPs) through a network of several temporary mobile blood units (MBUs) and permanent local blood centers (LBCs). In general, the strategic and tactical design of...
    Resource Type:
    Dissertation
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    different values of J and N. ...................................... 115 Figure 5.3: Variance of optimality

  • Crystallographic studies of Pyrenophora tritici-repentis ToxA

    Creator:
    Sarma, Ganapathy N.
    Abstract:
    Tan spot of wheat is an economically significant disease caused by the fungal pathogen, Pyrenophora tritici-repentis. Certain races of the fungus secrete Ptr ToxA (ToxA), a 13.2 kDa proteinaceous host-selective toxin that is responsible and sufficient to cause disease in susceptible wheat varieties. Disease symptoms develop only when the ToxA...
    Resource Type:
    Dissertation
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    -wheat interaction. Phytopathology 89, 444-449. 16 6. De Wolf, E. D., Effertz, R. J., Au, S. & Franci

  • Preparation and modification of cellooligosaccharides

    Creator:
    Akpinar, Ozlem
    Abstract:
    Cellooligosaccharides are the reaction intermediates produced during the hydrolysis of cellulose to glucose. Hence, they have the same chemical structure as cellulose, just shorter chain lengths. Cellooligosaccharides up to DP eight are soluble in water. The soluble cellooligosaccharides can be used "as is" in the food industry as non-digestible oligosaccharides...
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    Dissertation
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    . Michael H. Penner, for his time and support throughout my study. I owe special thanks to Dr. Robert J

  • Modeling protein structure at atomic resolution

    Creator:
    Berkholz, Donald S.
    Abstract:
    This thesis includes three studies involving different aspects of modeling protein structure. The first study illustrates the levels of insight available from atomic-resolution protein structures. The second study derives general trends of protein geometry from atomic-resolution structures and shows their implications for modeling. The third study creates a model of...
    Resource Type:
    Dissertation
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    glutathione reductase near 1 A resolution. J. Mol. Biol. 382, 371-384. Bradley, P., Misura, K.M.S., and

  • The effect of cytosine methylation on DNA structure

    Creator:
    Vargason, Jeffrey M.
    Abstract:
    DNA methylation is common in prokaryotes and eukaryotes and has been implicated in various biological roles including gene silencing, X-chromosome inactivation, and genomic imprinting. 5-methylcytosine the "fifth base" of the genetic code comprises 1-3% of the human genome and is primarily found on cytosines within the context of the CpG...
    Resource Type:
    Dissertation