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Filtering by: Creator Munts, Steven R. Degree Level Doctoral Non-Academic Affiliation Linus Pauling Institute

Characterization of the Mechanisms of Action and Molecular Targets of Hop-derived Flavonoids in the Mitigation of Obesity-related Metabolic Impairments

Creator:

Paraiso, Ines L.

Abstract:

Obesity is a complex multifactorial disease resulting from excessive energy intake compared to energy expenditure. The excess energy is mostly stored as fat in enlarged adipocytes, but some lipids may infiltrate other organs such as the liver to form ectopic fat. Adipose tissue and ectopic fat produce and secrete a...

Resource Type:

Dissertation

Full Text:

synthesis by reducing CYP7A1 expression via SHP, 2) decreases PCSK9 expression, thereby inducing LDL-R
Brassicas, microbes, and metabolites : a multi-omic investigation of cruciferous vegetable phytochemical metabolism

Creator:

Bouranis, John A.

Abstract:

Phytochemicals from cruciferous vegetables, such as broccoli, contain a multitude of bioactive compounds that prevent and suppress cancer and promote optimal health. Some of the health promoting effects of cruciferous vegetables are attributed to a class of compounds known as isothiocyanates (ITCs), a potent nuclear factor erythroid 2–related factor 2...

Resource Type:

Dissertation