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Filtering by: Creator Thompson, Gene Thomas Remove constraint Creator: Thompson, Gene Thomas Degree Level Doctoral Remove constraint Degree Level: Doctoral Non-Academic Affiliation Oregon State University. Center for Genome Research and Biocomputing Remove constraint Non-Academic Affiliation: Oregon State University. Center for Genome Research and Biocomputing

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  • Toxicogenomic Biomarkers Associated with PAH Carcinogenic Potential in a 3D in Vitro Bronchial Epithelial Model

    Creator:
    Chang, Yvonne
    Abstract:
    The environmental health science community recognizes polycyclic aromatic hydrocarbons (PAHs) as a re-emerging class of environmental pollutants due to their persistence and prominence in mixtures of concern. Due to their widespread distribution in the environment, exposure to PAHs often occur as complex chemical mixtures. Exposures are linked to numerous adverse...
    Resource Type:
    Dissertation
    Full Text:
    complex PAH mixture based on short-term biosignatures identified from global gene expression profiling

  • Investigating Transcriptional Control of Specialized Gene Expression in Plants

    Creator:
    Fraser, Valerie N.
    Abstract:
    Specialized or secondary metabolism is a collection of pathways and small molecules that, while beneficial to an organism, are not strictly necessary for survival. Plants use secondary metabolites to, among other things, attract pollinators, defend against biotic and abiotic stressors, and form symbioses. Natural products from plants have seen an...
    Resource Type:
    Dissertation
    Full Text:
    , 2021. Title: Investigating Transcriptional Control of Specialized Gene Expression in Plants

  • Comparative Transcriptomics in Stress-Induced Rice

    Creator:
    Al-Bader, Noor M.
    Abstract:
    Rice is an important crop that feeds almost half the world population. As climate change models predict floods, drought and extreme temperatures in rice production areas, the need to better understand the genetic basis of adaptation and tolerance to abiotic and biotic stresses is vital to sustain our food supply....
    Resource Type:
    Dissertation
    Full Text:
    , calling genetic variation, de-novo assembling transcript (mRNA) isoforms, differential gene expression

  • Transcriptomic Analyses of Crop Plants using Next-Generation Sequencing Technology

    Creator:
    Geniza, Matthew J.
    Abstract:
    Advancements in molecular biology and computer science have enabled researchers the ability to investigate the transcriptome – the quantification of an organism’s RNA transcripts in response to its environment on a system wide scale. The collective chapters of this thesis utilize high-throughput RNA sequencing, which produces hundreds of millions of...
    Resource Type:
    Dissertation
    Full Text:
    time, the T. monococcum transcriptomes were de novo assembled, annotated, and used to identify gene

  • Transcriptomic approaches for discovering regenerative and developmental regulatory networks in zebrafish

    Creator:
    Garland, Michael A.
    Abstract:
    Zebrafish are capable of fully regenerating organs and tissue such as their caudal fin, which is similar to a human regrowing an arm or a leg. In contrast, most mammals including humans have a greatly reduced capacity for wound healing. The ability of zebrafish to undergo this regenerative process, called...
    Resource Type:
    Dissertation
    Full Text:
    glucocorticoid beclomethasone diproprionate (BDP). We identified cripto-1 as a highly upregulated gene

  • Comparative Aquatic Toxicology of Pesticides and Plastics Using the Model Estuarine Fish, Inland Silverside

    Creator:
    Hutton, Sara J.
    Abstract:
    Based on current trends both pesticide and plastic production are expected to continue to rise in the coming decade. A growing global population coupled with the effects of climate change are the main drivers of increased pesticide use. Throughout this dissertation pesticides refer to herbicides, fungicides, and insecticides. Plastic production...
    Resource Type:
    Dissertation
    Full Text:
    . We measured growth, behavior, and changes in gene expression to compare the toxicity of the