Search Constraints

Start Over
Filtering by: Committee Member O'Neill, J. Philip Remove constraint Committee Member: O'Neill, J. Philip Degree Level Doctoral Remove constraint Degree Level: Doctoral Rights Statement In Copyright Remove constraint Rights Statement: In Copyright

Search Results

  • Mandelalides as Potent Mitochondrial ATP Synthase Inhibitors : From Discovery of New Analogs to Function-Oriented Synthetic Studies

    Creator:
    Nazari, Mohamad
    Abstract:
    Our quest for pharmaceutically important marine natural products led to re-isolation of known mandelalides A-D and identification of new congeners E-L from re-collected South African Lissoclinum tunicate specimens. Mandelalides A, B, and L were characterized as selective cancer cell toxins, with an unusual activity profile influenced by their glycosylation /...
    Resource Type:
    Dissertation
    Full Text:
    –1282. 39. Shair, M.; Yoon, T.; Mosny, K.; Chou, T.; Danishefsky, S. J. Am. Chem. Soc. 1996, 118

  • Advanced studies on cyclic amino acids in neurological signaling and peptide antibiotics

    Creator:
    Blanchard, David, L.
    Abstract:
    L-pipecolic acid (L-PA) is the higher homolog of proline. It occurs naturally in many organisms, including primates, as an intermediate in lysine degradation. The pathway by which lysine is converted into L-pipecolic acid employs the enzyme Lpipecolate oxidase (L-PO), and appears to be tissue specific to the central nervous system...
    Resource Type:
    Dissertation
    Full Text:
    : Dr. Philip Proteau, Dr. Taifo Mahmud, Dr. Xihou Yin, and Dr. Thomas Savage for their proofreading

  • The cohomology rings of seven dimensional primitive cohomogeneity one manifolds

    Creator:
    Ultman, Shari K.
    Abstract:
    A striking feature in the study of Riemannian manifolds of positive sectional curvature is the narrowness of the collection of known examples. In this thesis, we examine the structure of the cohomology rings of three families of compact simply connected seven dimensional Riemannian manifolds that may contain new examples of...
    Resource Type:
    Dissertation
    Full Text:
    family O(p,q:m). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 4 PROOFS OF THEOREMS

  • Heavy fermion effective mass in the superconducting vortex state

    Creator:
    Townsend, Emily A.
    Abstract:
    The extended-Lifshitz-Kosevitch formalism (ELK) unifies the treatment of the de Haas-van Alphen (dHvA) effect, allowing it to transcend its traditional roles of mapping Fermi surfaces and measuring effective masses. Here we exploit the capabilities of dHvA as a probe of many-body effects to examine heavy-fermion su- perconductivity. ELK successfully describes...
    Resource Type:
    Dissertation
    Full Text:
    electron in the problem has good total angular momentum, J , which is either l + s = 7 2 or l− s = 5 2

  • Quantifying the Unproductive Water Lost as Evaporation from Different Irrigation Designs by Analysis of the Soil Stable Water Isotope Compositions

    Creator:
    Al-Oqaili, Firas M.
    Abstract:
    The knowledge about the intensive agricultural irrigation is very limited, but the use of irrigation is rapidly increasing. As an outcome, the sympathetic ecosystem is accepting modern irrigation that will play an essential function in the present and future for agricultural products. My dissertation will display the modification for investigation...
    Resource Type:
    Dissertation
    Full Text:
    , the average isotope ratio of soil water under LESA irrigation (δD= -114.5‰, δ18O= -14.5‰) had lower

  • Development of Methods for Stereoselective Carbon-Carbon Bond Formation

    Creator:
    Wu, Zhenhua
    Abstract:
    Three distinct methods to achieve the stereoselective synthesis of carbon-carbon bonds were investigated, encompassing: (i) the formation of axially chiral biaryl molecules by enantioselective Suzuki cross-coupling, (ii) the synthesis of α-phenylalkylboronic esters by enantioselective chain extension, and (iii) the stereospecific synthesis of alkenes by eliminative cross-coupling of enantioenriched sp³-hybridized carbenoids....
    Resource Type:
    Dissertation
    Full Text:
    boronates with a combination of O- (-lithiobenzyl)-N,N-diisopropylcarbamate and ligand 3,3-bis[(4S)-4,5

  • A study of values of educators in Oregon's correctional institutions

    Creator:
    Colbert, Austin Michael
    Abstract:
    The purpose of this study was to measure the relative prominence of the values -- theoretical, economic, political, aesthetic, social, and religious--among the four groups of institutional educators under the direction of the State of Oregon Corrections Division in the two adult and two juvenile facilities; namely, the Oregon State...
    Resource Type:
    Dissertation
    Full Text:
    Isabella F. McQuesten for not only being a committee member, but a true friend; Dr. J. Philip O'Neill

  • A study of the relationship of the use of various drugs to the visual-motor performance of college students

    Creator:
    Antone, Eugene Joseph, Jr.
    Abstract:
    The purpose of the study was to compare the visual-motor performance of college students who reported ingestion of certain drugs with those college students who reported no drug ingestion. The study drugs included the following drugs or groups of drugs: tobacco, alcohol, marijuana, LSD, mescaline, barbiturates, and amphetamines. A total...
    Resource Type:
    Dissertation
    Full Text:
    . Anderson, Professor of Health Education; Dr. J. Philip O'Neill, Professor of Family Life; Dr. Howard L

  • Biosynthesis and modification of the antibiotic enduracidin

    Creator:
    Goebel, Neal C.
    Abstract:
    The continued propagation of antibiotic resistance requires the development of new therapeutics. The lipopeptide antibiotic enduracidin has demonstrated high activity against Gram-positive pathogens including methicillin-resistant Staphylococcus aureus. In addition to a lack of cross-resistance with existing antibiotic classes, enduracidin has no known transferrable resistance mechanism. The development of enduracidin as...
    Resource Type:
    Dissertation
    Full Text:
    N S H N H O OH O O N N NH2 NH2 S H2N O O NH2 S H2N O O Figure 1.1 A) Structure of

  • Synthesis and study of oxides and chalcogenides : thin films and crystals

    Creator:
    Park, Sangmoon
    Abstract:
    Several types of solid-state inorganic materials are prepared and characterized. By using the SILAR (Successive Ionic Layer Adsorption and Reaction) deposition method in conjunction with hydrothermal dehydration both low-temperature deposition and crystallization of oxide thin films are achieved. Various aspects of new transparent p-type materials are studied by examining both...
    Resource Type:
    Dissertation
    Full Text:
    appreciation to my Ph.D. committee members and former committee members: Dr. Arthur W. Sleight, Dr. Philip R