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Filtering by: Creator Townsend, M. Shaun Degree Level Doctoral Subject Cancer -- Chemoprevention

Mechanisms of inhibition of chemical carcinogenesis by indole-3- carbinol in the rat

Creator:

Stresser, David M.

Resource Type:

Dissertation

Full Text:

indole-3- carbinol in the rat AN ABSTRACT OF THE THESIS OF David M. Stresser for the degree of Doctor
Critical windows of transplacental carcinogenesis : identifying efficacious approaches to chemoprevention with dietary phytochemicals

Creator:

Castro, David J.

Abstract:

Polycyclic aromatic hydrocarbons (PAHs) are a re-emerging class of environmental pollutants. The persistent nature of these highly toxic compounds along with their ubiquity in the environment creates an unavoidable route of exposure. The developing fetus and neonate are a particularly susceptible population due to their incomplete complement of xenobiotic metabolizing...

Resource Type:

Dissertation

Full Text:

2,3,4. Drs. Katrina M. Waters and Bobbie-Jo Webb-Robertson provided the statistical modeling and
Chronic exposure of rodents to indole-3-carbinol and 3,3'-diindolylmethane : implications for drug metabolism, chemoprevention and human health

Creator:

Leibelt, Dustin A.

Abstract:

Indole-3-carbinol (I3C) is a naturally occurring plant alkaloid, found in significant concentrations in cruciferous vegetables such as broccoli and Brussels sprouts. I3C is an unstable compound that undergoes rapid oligomerization in an acidic environment to form higher order condensation products (I3C-ACPs), such as 3-3'-diindolylmethane (DIM). Both I3C and DIM are...

Resource Type:

Dissertation

Full Text:

hydroxylation. Biochem. Pharmacol. 45, 1129-1136. Jin, L., Qi, M., Chen, D.Z. Anderson, A., Yang, G.Y., Arbeit