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Filtering by: Advisor Warnes, William H. Remove constraint Advisor: Warnes, William H. Degree Level Doctoral Remove constraint Degree Level: Doctoral Subject Marine pharmacology Remove constraint Subject: Marine pharmacology

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  • Bioactive secondary metabolites from marine algae and study of oxidized anandamide derivatives

    Creator:
    Yoo, Hye-Dong
    Abstract:
    My investigations of the natural products of marine algae have resulted in the discovery of several new secondary metabolites. Bioassay-guided fractionation led to the isolation of these new compounds and spectroscopic analysis was utilized in their structural characterization. Two new and potent antimitotic metabolites, curacins B and C, were isolated...
    Resource Type:
    Dissertation
    Full Text:
    from Marine Algae and Study of Oxidized Anandamide Derivatives Abstract approved: William H. Gerwick

  • Natural products studies of the marine cyanobacterium Lyngbya majuscula

    Creator:
    Sitachitta, Namthip
    Abstract:
    The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich in bioactive secondary metabolites. This dissertation describes the chemistry of L. majuscula collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites, curacin A and barbamide. The chemical studies with a Grenada collection...
    Resource Type:
    Dissertation
    Full Text:
    ------------ William H. Gerwick The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich

  • Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

    Creator:
    Milligan, Kenneth Edward
    Abstract:
    This thesis describes investigations of marine algal secondary metabolites, with particular interest in their biomedical and agrichemical potential. Invaluable in such pursuits have been the access and application of advanced spectroscopic techniques, such as NMR, and the ability to assess the biological activity of the algal samples in a variety...
    Resource Type:
    Dissertation
    Full Text:
    Secondary Metabolites of Unique Structure and Biomedicinal or Agrichemical Potential. Abstract William H

  • Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

    Creator:
    Marquez, Brian L.
    Abstract:
    This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngbya majuscula. In addition, biosynthetic investigations were undertaken using stable isotope-labeled precursors. The dominant role that NMR spectroscopy plays...
    Resource Type:
    Dissertation
    Full Text:
    Cyanobactenal Natural Products: Development and Application of New NMR Methods. Abstract approved: William H