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Filtering by: Subject Antibiotics -- Synthesis Remove constraint Subject: Antibiotics -- Synthesis Degree Level Doctoral Remove constraint Degree Level: Doctoral Subject Microbial metabolites Remove constraint Subject: Microbial metabolites

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  • Biosynthetic engineering of new pactamycins

    Creator:
    Lu, Wanli
    Abstract:
    Among the myriad of naturally occurring bioactive compounds are the aminocyclopentitol-containing natural products that represent a family of sugar-derived microbial secondary metabolites, such as the antibiotics pactamycin, allosamidin, and trehazolin. Pactamycin, a structurally unique aminocyclitol antibiotic isolated from Streptomyces pactum, consists of a 5-membered ring aminocyclitol (cyclopentitol) unit, two aromatic...
    Resource Type:
    Dissertation
    Full Text:
    unique aminocyclitol antibiotic isolated from Streptomyces pactum, consists of a 5- membered ring