The primary goal of my studies was to elucidate the mechanisms for the well-recognized interaction between two nutrients, vitamins E and K. The outcomes from my studies assess mechanisms for adverse effects of vitamin E and provide novel information on mechanisms for vitamin K homeostasis. These findings will provide information...
Compounds belonging to the vitamin K family possess anti-hemorrhagic
property, and are used in treating patients suffering
from hypoprothrombinemia and obstructive jaundice. Some of
these compounds also exhibit marked antimicrobial activity toward
various microorganisms. Vitamin K₅, 4-amino-2-methyl-
1-naphthol hydrochloride, a water-soluble analog of vitamin K
has been shown to possess...
The metabolic fate of cholesterol delivered to rat hepatocytes by rat plasma lipoproteins was determined. Binding and degradation of rat low and high density lipoproteins (LDL and HDL) in rat hepatocytes were studied. ¹²⁵I-labelled LDL and HDL were incubated with cells in the presence of varying concentrations of unlabelled lipoproteins...
The effects of various physical parameters on the binding, uptake,
and catabolism of glucose in the marine psychrophilic bacterium,
Vibrio marinus, were studied. It was shown that shortly after
the cell was exposed to labeled glucose, the radioactive label became
rapidly associated with the cell fraction. It was also shown...
In this dissertation, the process of computational modeling of amorphous oxide materials is studied. Amorphous oxides have random atomic arrangements with no long-range structural order which makes it difficult to study structure-property relationships. Despite the difficulties, amorphous oxides have great uses as semiconductors and dielectrics in thin-film transistors. The ability...
The dissertation examines the effect of two separate yet significant individual level factors—physical and cognitive traits—on entrepreneurial outcomes. The physical factor on which the dissertation focuses is the entrepreneur’s vocal cues and the cognitive traits that the dissertation investigates are the entrepreneur’s goal orientation and his/her ability to take perspectives....
In this three-essay dissertation I explore how CEOs’ self-serving motivation, specifically driven by their relative pay standing and celebrity status, is useful for advancing the understanding of executive behavior and strategic decision-making. In the first essay, focusing on CEOs’ motivation to reduce the dissonance caused by pay inequity, I examine...
Innovation is critical for firm growth and survival. Thus, how much value firms create and capture from their innovative activities has been an interest of scholars. This dissertation explores three important questions on this topic to which extant literature has paid little attention. First, I examine how the external threat...
This dissertation was a qualitative case study focused on part-time faculty teachingdevelopmental mathematics courses in one large Pacific Northwest community college. Thecollege was selected for its size and maturity; the topic was selected for three related reasons:part-time faculty have been widely relied upon to teach these courses nationwide; students indevelopmental...