The spectrophotometric titration of the tyrosine residues,
their reaction with N-acetylimidazole, and the effect of pH on the
thermally induced conformational transition of ribonuclease T₁ have
been investigated. The results of spectrophotometric titration in
0.20 M KCl/0.001 M sodium phosphate suggest that titration of the
tyrosine residues occurs in two...
The immune toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been studied for over 35 years, but only recently has the profound immune suppression associated with TCDD exposure been linked to induction of regulatory T cells (Tregs). The effects of TCDD are mediated through binding the aryl hydrocarbon receptor (AhR), a ligand-activated transcription...
Proper immune function is indispensable, as failure to mount an immune response against a pathogen can lead to serious complications or even death. T cells act by enhancing the activation of phagocytic cells as well as the activation of B cells. Their widespread influence on an immune response makes optimal...
The differential cross section for the reaction k⁻+p[forward arrow] k⁰+[uppercase xi]⁰ was measured in a spark chamber experiment for an incident k⁻ momentum of 1.8 GeV/c. The target was liquid hydrogen confronted
by an anti-coincidence counter to insure neutral particle production.
A 60 element hodoscope signalled the presence of four...
The aryl hydrocarbon receptor (AhR) has recently been described as a novel therapeutic target, given the potent suppression of multiple immune-mediated diseases following activation by the prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In the parent-into-F1 graft-versus-host (GVH) model, suppression of the cytotoxic T-lymphocyte (CTL) response is associated with the presence of CD25⁺CTLA-4⁺IL-10⁺Foxp3[superscript...
A study of populations characteristics of T. turgidum ssp.
carthlicum and T. aestivum ssp. carthlicoides was completed using
numerical analysis. A sample of 74 accessions of ssp. carthlicum
and 20 of ssp. carthlicoides were scored for 46 characters. It was
established that three morphological distinguishable groups of ssp.
carthlicum can...
Electrodeposition is a versatile polymer deposition technique to create nano-microscale materials using an electrical field generated from a charged droplet of solution and a grounded collector. Electrospinning or electrospraying can occur during electrodeposition, leading to the creation of nanofibers or bead-like materials depending on the process parameters. Photopolymerization of the...
Compounds belonging to the vitamin K family possess anti-hemorrhagic
property, and are used in treating patients suffering
from hypoprothrombinemia and obstructive jaundice. Some of
these compounds also exhibit marked antimicrobial activity toward
various microorganisms. Vitamin K₅, 4-amino-2-methyl-
1-naphthol hydrochloride, a water-soluble analog of vitamin K
has been shown to possess...