Microchannel process technology (MPT) offers several advantages to the field of nanomanufacturing: 1) improved process control over very short time intervals owing to shorter diffusional distances; and 2) reduced reactor size due to high surface area to volume ratios and enhanced heat and mass transfer. The objective of this thesis...
High temperature microchannel heat recuperators (HTμRs) offer an efficient means of improving reactor process thermal efficiency by offering smaller form factors due to increased heat transfer surface area density and volumetric heat transfer rate over traditional heat exchanger designs. To date, HTμRs face cost and reliability challenges. In this work,...
Five forms of chromatin, which represent the in vivo folded forms
of nucleic acid, were isolated and used as the binding substrate for
model intercalating compound, ethidium bromide. For all forms of
chromatin, the affinity, location and structural effects of binding
were examined. On the level of the nucleosome, the...
The research examines the effect of restricted head and neck movement on
driving performance as measured by decision time at T-intersections. The traffic
safety and human factors literature was reviewed, and very little was found
concerning drivers with physical limitations. T-intersections were selected for
study because most accidents involving drivers...
A microfluidic nanofiltration module has been designed, fabricated and applied to the continuous-flow, pressure-driven, post-synthetic purification of macromolecules and nanoparticles via diafiltration using a commercially available organic solvent resistant nanofiltration membrane, STARMEM 122. This module will readily interface with other microscale components within a
"nanofactory" for the rapid synthesis, purification...
Incubation experiments with an acid poorly drained soil have
shown that the application of neutral soluble salts influenced the level
of extractable Mn. The application of a salt which lowered the soil
pH either increased the extractable Mn or retarded the oxidation
and/or fixation of extractable Mn. This effect was...
Human alterations of landscapes take many forms, one of which is anthropogenic pollution. Mercury (Hg) is a complex contaminant because its uptake into the food web is not driven entirely by loading to the system; methylation is necessary to make Hg bioavailable and toxic to fish and wildlife. Because methylation...
The goal of this dissertation was to improve our abilities in acquiring critical in vivo data by establishing embryo-larva zebrafish as an exemplary model to quantitatively evaluate cancer progression. The living environment that encompasses a tumor has a significant effect on how cancer develops, grows and metastasizes. In order to...