In areas such as spatial analysis and time series analysis, it is essential to understand and quantify spatial or temporal heterogeneity. In this dissertation, we focus on a spatially varying coefficient model, in which spatial heterogeneity is accommodated by allowing the regression coefficients to vary in a given spatial domain....
Wireless Networks have been widely adopted into a major part of today's network infrastructure. They have become a popular technology to not only expand the coverage of wired networks but also to interconnect a large wireless network, i.e., wireless mesh networks. As they allow more flexible communication than traditional wired-networks...
Symbiosis is the close and protracted interaction between organisms. The molecular interactions that occur during symbiosis are complex with multiple barriers that must be overcome. Many Gram-negative, host-associated bacteria use a type III secretion system to mediate associations with their eukaryotic hosts. This secretion system is a specialized apparatus for...
Oomycetes are some of the most devastating pathogens, causing upwards of billions of dollars of damage each year to plants. They also diminish ecological diversity and health through the destruction of trees and shrubs. The genome sequence of Pseudoperonospora cubensis, an obligate plant pathogen and causative agent of downy mildew...
Cardiovascular disease (CVD) is the leading cause of mortality in the United States (US) and research suggests that CVD morbidity and mortality disproportionately impacts Asian American and Native Hawaiian and Pacific Islander (NHPI) older adults. However, the prevalence on CVD and underlying mechanisms for CVD disparities among disaggregated Asian American...
There is an emerging interest in developing wearable electronics as a platform, which
provides the flexibility of a wearable while maintaining its promising functionality as smart textiles. Metal-halide semiconductors are attractive materials with tunable optical and electrical properties. Researchers have widely studied and applied it for advanced
photonics and optoelectronic...
Symbioses between microbes and multicellular eukaryotes are found in all biomes, and encompass a spectrum of symbiotic lifestyles that includes parasitism and disease, commensalism, and mutually beneficial interdependent host-microbe relationships. Regardless of outcome, these symbiotic lifestyles are governed by a complex molecular "courtship" between microbe and potential host. This courtship...
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Jeff H. Chang
Symbioses between microbes and multicellular eukaryotes are found in all
Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
This thesis concerns itself mainly with analytical methods
development and analytical applications in the field of drug metabolism
studies. The determination of the analgesic pentazocine and its
metabolites in the greyhound are studied.
Pentazocine and all of its possible metabolites are isolated from
the greyhound urine by a the multi-solvent...
The effects of selected family characteristics on
interrelated components of household asset portfolios over a
three-year time period were investigated. Specifically, this
study attempted to conceptually define mental accounts, to
identify own-adjustment and cross-adjustment characteristics
of these mental accounts, to explore influences of selected
family characteristics on these mental accounts,...
Pseudomonas syringae are plant pathogenic bacteria that cause disease by rapidly multiplying within the aboveground tissues of host plants. Growth of P. syringae within plant host tissues requires the disarmament of host immune defenses that limit microbial growth. To combat host defenses, P. syringae deploys a type III secretion system...
Gall-associated phytopathogens have unique evolutionary histories that haveshaped both their modes of infection and genomic structures. Pathogenicity of the gall-associated plant pathogens of the Rhodococcus, Agrobacterium, and Rathayibactergenera is mediated by horizontally acquired virulence loci. The relative ease of gainand loss of the virulence loci has confounded accurate characterization of...
Copper sulfides (Cu[subscript x]S) are compound semiconductor materials that exhibit considerable optical and electrical properties varying significantly as a function of the composition. Copper sulfide thin films can be used in many applications, such as solar control coatings, solar cells, photothermal conversion of solar energy, electroconductive coatings, and microwave shielding...
To understand how a Depressurized Loss of Forced Convection (D-LOFC) initiated from a double-ended guillotine break may affect further operation of a High Temperature Gas Cooled Rector (HTGR), thorough understanding of each specific stage of this event is required. Key considerations that need to be determined is the amount of...
This study was undertaken to analyze the opinions of
elementary school teachers in Korea about actual and desired
levels of computer education and the sources of computer
anxiety, with the object of developing guidelines for
a teacher training program. A survey instrument was developed
and tested to provide basic sample...
The environmental health science community recognizes polycyclic aromatic hydrocarbons (PAHs) as a re-emerging class of environmental pollutants due to their persistence and prominence in mixtures of concern. Due to their widespread distribution in the environment, exposure to PAHs often occur as complex chemical mixtures. Exposures are linked to numerous adverse...
Analysis of observations on sequential events over time is common in real life. Sequential measurements over time describing the behavior of systems are usually called time series data, which have been collected in a wide range of disciplines. Over the years there have been multiple research areas in studying stochastic...
Diverse scientific fields collect multiple time series data to investigate the dynamical behavior of complex systems: atmospheric and climate science, geophysics, neuroscience, epidemiology, ecology, and environmental science. Identifying patterns of mutual dependence among such data generates valuable knowledge that can be applied either for inferential or forecasting purposes. Vector autoregressive...