Human cathelicidin antimicrobial peptide (CAMP/LL-37) is a cationic antimicrobial peptide that is widely expressed by myeloid and epithelial cells at the human-environment interface. It possesses broad spectrum antimicrobial capacity against bacteria, fungi and viruses. In addition to its direct antimicrobial activity, CAMP/LL-37 also attracts and recruits monocytes, neutrophils and other...
Forests face health threats from pests and diseases (e.g., mountain pine beetle, emerald ash borer, chestnut blight [CB], Swiss needle cast), and other issues such as climate change. Interventions such as genetic engineering (GE) have shown promise for mitigating some of these threats. CB, for example, has impacted most American...
:
_____________________________________________________________________
MarkD. Needham
Forests face health threats from pests and diseases (e.g., mountain pine
The number of people traveling to other countries to volunteer for conservation or humanitarian projects has increased dramatically in the past three decades. Despite substantial interest in volunteer tourism, few researchers have examined: (a) the role of promotional material (e.g., brochures, internet websites) in motivating volunteers; (b) factors that attract...
Vibriosis caused by the bacterial pathogen Vibrio tubiashii is one of several factors contributing to mass larval mortalities of the Pacific oyster (Crassostrea gigas) in Pacific Northwest shellfish hatcheries in recent years. Genetically improved strains of the Pacific oyster resistant to V. tubiashii would be highly desirable. This study investigates...
African rhinoceros, once abundant across Africa, face threats to their long-term survival primarily due to the syndicated poaching of their horns for Traditional Asian Medicine and as status symbols in Asia. Most studies focusing on the human dimensions of rhinoceros poaching have been limited to examining a few aspects of...
The purpose of this manuscript style dissertation was to increase understanding of the experiences of counselor's with compassion fatigue as they participated in a yoga intervention. Compassion fatigue is a condition that creates both physical and psychological impairment as a result of working in the helping role. Yoga is an...
Alfalfa sprouts have been implicated in several salmonellosis outbreaks in recent years. Electrolysis of a NaCl solution generates, in the anode side of a two-chamber electrolyzer, acidic electrolyzed oxidizing (EO) water which contains Cl₂, HOC1, dissolved oxygen, and it is characterized by a low pH and a high oxidation reduction...
School administrators are required by law to report suspected cases
of child abuse. They create serious legal and moral consequences for their
school districts when they fail to report suspicions of child abuse occurring
in the school setting. Studies consistently find that child sexual abuse is
under-reported and that allegations...
Invasive species are a growing global economic and ecological problem. Invasive Indo-Pacific lionfish (Pterois spp.) are known to have extreme negative effects on coral-reef communities in the Bahamas, so understating their distribution within and among reefs, what limits their local movements, and the effects they have on native prey species...
Understanding the dynamics of open marine populations is difficult. Ecological processes may vary with the spatial structure of the habitat, and this variation may subsequently affect demographic rates. In a series of observational and experimental studies in the Bahamas, I examined the roles of emigration, mortality, and predation in the...
Peroxisome proliferator-activated receptors (PPARs) are members of a
large group of ligand-regulated transcription factors that includes nuclear
receptors for steroid and thyroid hormones, retinoids and vitamin D₃.
Synthetic fibrates and thiazolidinediones that bind to and activate PPARs are
used efficaciously in humans to remedy hypertriglyceridemia and non-insulin
dependent diabetes mellitus,...
There is substantial interest in the application of mindfulness in counseling and psychotherapy. The appeal of mindfulness training and mindfulness-based interventions has increased as research continues to demonstrate benefits. Mindfulness practice has not only been effective in clinical applications with clients, but has also been conceptualized as beneficial for counselors...
How the direct and indirect effects of species interactions cascade to affect community structure, functioning, and stability is a fundamental question in ecology. In temperate kelp forests, species interactions, in conjunction with environmental processes, produce rich spatiotemporal dynamics.
Arguably the most dramatic of these are abrupt shifts in community state,...
BCL11B is a transcriptional regulatory protein that plays essential roles during mouse embryonic development. BCL11B is expressed and functions in the immune and nervous systems as well as within ectodermal organs. Multiple studies have characterized the roles of BCL11B in T cells, brain, and skin. However, very little is known...
Studies using the pluripotent embryonic carcinoma cell line, P19, as a retinoic acid (RA)-responsive model system have been instrumental towards our understanding of the RA-dependent signaling pathways in development and homeostasis. Grp1-associated scaffold protein (GRASP; also known as Tamalin) was first identified by our group, as a gene robustly induced...
:
________________________________________________________________________
Mark Leid
Studies using the pluripotent embryonic carcinoma cell line, P19, as a