RNA silencing pathways are required for a wide variety of processes in most
eucaryotes. In plants, small-interfering RNA (siRNA) arising from transposons and other
repetitive sequences is associated with heterochromatin formation and maintenance.
MicroRNAs and trans-acting siRNAs encoded at discrete loci function as negative regulators of
gene expression by triggering...
In this dissertation, multi-rate array (MRA) architecture and its synthesis are proposed
and developed. Using multi-coordinate systems (MCS), a unified theory for mapping
algorithms from their original algorithmic specifications onto multi-rate arrays is
developed.
A multi-rate array is a grid of processors in which each interconnection may have its
own...
Eukaryotic small RNA (~20-30 nucleotides) are diverse regulatory molecules that repress gene expression at the transcriptional and post-transcriptional levels, defend hosts against invading viruses and defend genomes against selfish DNA elements. Small RNA populations are studied by high-throughput sequencing of the total small RNA fraction isolated from cells, however, the...
Better performance has been one of the main motivations behind the recent resurgence
of interest in asynchronous circuits (no matter whether this is always true or not).
We are particularly interested in the performance of pipelines since they are used extensively
in current digital systems. There exists an algorithm that...
RNA interference pathways can involve amplification of secondary siRNAs by RNA-dependent RNA polymerases. In plants, RDR6-dependent secondary siRNAs, including transacting siRNAs (tasiRNAs), arise from transcripts targeted by some microRNAs (miRNAs). In the case of TAS3 tasiRNA formation, ARGONAUTE7 (AGO7)-miR390 complexes interact with primary transcripts at two sites, resulting in recruitment...
Fluctuations and spatial heterogeneity of habitat and resources is thought to underlie niche variation in animal populations, with intraspecific differences serving to produce or maintain population-, community-, or ecosystem-level patterns. Individual diet variation, defined as individual variation in food resource use within a population that is consistent over time, is...