This dissertation delves into understanding, characterizing, and addressing dataset shift in deep learning, a pervasive issue for deployed machine learning systems. Integral aspects of the problem are examined: We start with the use of counterfactual explanations in order to characterize the behavior of deep reinforcement learning agents in visual input...
The Indian Ocean Experiment (INDOEX) had as a primary objective
determining the radiative forcing due to anthropogenic aerosols over
climatologically significant space and time scales: the Indian Ocean during the
winter monsoon, January-March. During the winter monsoon, polluted, low-level
air from the Asian subcontinent blows over the Arabian Sea and...
The effect of ultra-high pressure on the thermal emf of a
chromelialumel thermocouple is investigated using an indirect
method which does not require a direct knowledge of the temperature
of the pressurized junction. The unknown temperature is written
parametrically as a function of a directly measured quantity, the
electrical power...
Escherichia coli 16S-like ribosomal RNAs from
eubacterial, archaebacterial and eukaryotic organisms have
several universally conserved sequence zones which are
proposed to be single-stranded. A clear function for all
of these regions has not yet been defined. To evaluate the
roles of these sequence zones in protein synthesis,
knowledge of their...
Purpose: Model-based dose calculation algorithms (MBDCAs) have become clinically available within the past several years in commercially available brachytherapy planning systems. This work investigates the application of a 510(k) approved MBDCA Acuros™ BV and establishes a reproducible method of validation. The research is broken into three primary research goals. The...
The in vitro effects of cortisol in regulating salmonid B cell functions were
investigated. B cells at three distinct stages of differentiation were examined for
cortisol sensitivity. B lymphocyte responses were examined 1) during the early stage
of the precursor, 2) during the intermediate stage of differentiation associated with
clonal...
Electric power needs will only grow over the next decades as more humans ascend from poverty into the middle class. Currently, the majority of electric power is generated by burning fossil fuels. To help mitigate the undesirable effects of burning fossil fuels research is being done to increase the efficiency...
In this dissertation, the spectroscopic properties and thermodynamic stability of a class of materials known as metal oxo and hydroxo clusters are studied. In aqueous solutions, many metals can aggregate into discrete clusters of metals bridged by oxo or hydroxo ligands. These clusters are of particular interest to us for...
The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...