Index Catalog // ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Creator:: Maxwell, Joseph R.
Abstract:: T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
Resource Type:: Dissertation
Full Text:: Costimulation and Adjuvants in the Development of T Cell Effector and Memory Responses. Abstract approved

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

Creator:: Shepherd, David M.
Abstract:: The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
Resource Type:: Dissertation
Full Text:: -Tetrachlorodibenzo-p-dioxin on T Cell Activation by David M. Shepherd A DISSERTATION submitted to

An Investigation into the Functional Properties of the Deafness Causing Protein Otoferlin

Creator:: Manchanda, Aayushi
Abstract:: Otoferlin is a C2-domain, transmembrane protein whose mutated form is responsible for the DFNB9 subtype of prelingual hearing impairment. Mutations in otoferlin cause an autosomal recessive, non-syndromic form of deafness that is characterized by auditory neuropathy/ auditory dissynchrony (AN/AD), meaning that the outer hair cells (OHCs) are normal, and the...
Resource Type:: Dissertation
Full Text:: . Johnson Abstract Otoferlin is a C2-domain, transmembrane protein whose mutated form is

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

Creator:: Prell, Rodney A.
Resource Type:: Dissertation
Full Text:: of 2,3,7,8-tetrachlorodibenzo-p- dioxin-Induced Immunotoxicity in C57B1/6 Mice: Effects on T Cell

Vitamin E and K interactions : investigating mechanisms of reduced vitamin K status in response to excess vitamin E

Creator:: Farley, Sherry Mae
Abstract:: The primary goal of my studies was to elucidate the mechanisms for the well-recognized interaction between two nutrients, vitamins E and K. The outcomes from my studies assess mechanisms for adverse effects of vitamin E and provide novel information on mechanisms for vitamin K homeostasis. These findings will provide information...
Resource Type:: Dissertation
Full Text:: no increases in urinary vitamin K catabolites were found. Chapter 4 shows that -T-injected rats

The influence of aryl hydrocarbon receptor activation on T cell fate

Creator:: Funatake, Castle J.
Abstract:: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
Resource Type:: Dissertation
Full Text:: Hydrocarbon Receptor Activation on T Cell Fate. approved: 2,3,7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) and

T lymphocyte death as a potential mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immune suppression

Creator:: Dearstyne, Erica A.
Resource Type:: Dissertation
Full Text:: -tetrachlorodibenzo-p-dioxin (TCDD or dioxin). T lymphocyte- dependent responses are particularly sensitive to the

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B(SEB)-induced alterations in T-cell activation and cytokine production

Creator:: Huang, Wentian
Resource Type:: Dissertation
Full Text:: -Tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B (SEB)-Induced Alterations in T-Cell Activation

The divergent k-plane transform

Creator:: Keinert, Fritz
Abstract:: See pdf.
Resource Type:: Dissertation
Full Text:: p(t) (1t2)(k-3)12 dt = C < m, Gk-1(V) then Ta is undefined for a rk-1(9), but this is a

Empirical Analyses of Forestry Interactions with Climate Uncertainty and Threatened Species

Creator:: Johnson, Kelsey K.
Abstract:: Forests are highly valuable resources providing both timber as well as many non-use values like habitat for various endangered and threatened species, carbon sequestration, and recreation, to name a few. Given that there are 765 million acres of forestland in the United States, almost 60% of which are privately owned,...
Resource Type:: Dissertation

ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

An Investigation into the Functional Properties of the Deafness Causing Protein Otoferlin

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

Vitamin E and K interactions : investigating mechanisms of reduced vitamin K status in response to excess vitamin E

The influence of aryl hydrocarbon receptor activation on T cell fate

T lymphocyte death as a potential mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immune suppression

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B(SEB)-induced alterations in T-cell activation and cytokine production

The divergent k-plane transform

Empirical Analyses of Forestry Interactions with Climate Uncertainty and Threatened Species

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