Melanoma is the deadliest form of skin cancer, arising from malignant transformation of pigment-producing melanocytes. The primary risk factor for melanoma and other skin cancers is DNA damage resulting from unprotected solar ultraviolet radiation (UVR). If incorrectly repaired, this damage can result in incorporation of mutations that cause aberrant cell...
Powder Bed Fusion (PBF) techniques are additive manufacturing (AM) technologies with paradigm-shifting potential for the production industry. However, before they can become viable production solutions for quality critical industries, issues with process consistency and repeatability need to be addressed. There is a need for in-situ sensing systems that characterize process...
Fine roots are a dynamic component of Douglas-fir ecosystems. Changes in standing crops indicate that fine roots require a major portion of the stand's energy resources to fulfill their role in the
functioning of these systems. We observed standing crops of live and dead fine (< 1 mm diameter) and...
In this thesis we develop a theoretical framework for the identification of situations where the equal frequency (EF) or equal variance (EV) subclassification may produce lower bias and/or variance of the estimator. We conduct simulation studies to examine the EF and EV approaches under different types of model misspecification. We...
Aquatic animals are exposed to a variety of natural and
anthropogenic xenobiotics. Biotransformation of xenobiotics was
examined in three aquatic animals: a primitive mollusc (chiton);
a shellfish which is an important human food source (oyster);
and, a lower vertebrate model for toxicological studies (rainbow
trout). Since digestive glands of Cryntochiton...
A series of studies, in three western Oregon Douglas-fir plantations, was conducted to understand the physiological impacts of Swiss needle cast on Douglas-fir physiology. Four aspects of the disease complex were investigated: fungal colonization and assessment, plant-water relations, carbon assimilation and interaction with climate. Several techniques were developed and used...
Butane-grown Pseudomonas butanovora oxidized butane by a soluble butane monooxygenase through the terminal pathway yielding 1 -butanol as the predominant product. Alcohol dehydrogenases (ADHs) involved in butane oxidation in P. butanovora were purified and characterized at the biochemical, genetic and physiological levels. Butane-grown P. butanovora expressed a type I soluble...
The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...
The prevalence of childhood illness requiring hospitalization establishes the need for implementation of an applied intervention to decrease levels of hospitalization-induced anxiety in pediatric patients. In addition to anxiety, levels of perceived trauma have also been linked to pre-operative pediatric patients. Child-Centered Play Therapy (CCPT) within the medical setting has...
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Daniel Stroud
The prevalence of childhood illness requiring hospitalization establishes
