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Filtering by: Creator Ogawa Abe, Tania Marie Degree Level Doctoral

Oxidative stress in amyotrophic lateral sclerosis : the role of cellular senescence and glutathione

Creator:

Beilby, Pamela R.

Abstract:

Amyotrophic lateral sclerosis (ALS) is a devastating neurological disorder characterized by neuromuscular junction decay, motor neuron death, progressive paralysis, and eventually death of the individual, usually by respiratory failure. Oxidative stress is a prominent hallmark of the disease and is often accompanied and exacerbated by mitochondrial dysfunction and neuroinflammation. This...

Resource Type:

Dissertation
Transcriptomic Analyses of Crop Plants using Next-Generation Sequencing Technology

Creator:

Geniza, Matthew J.

Abstract:

Advancements in molecular biology and computer science have enabled researchers the ability to investigate the transcriptome – the quantification of an organism’s RNA transcripts in response to its environment on a system wide scale. The collective chapters of this thesis utilize high-throughput RNA sequencing, which produces hundreds of millions of...

Resource Type:

Dissertation