Most parasites and their hosts live in a balance within their environment; however a disease outbreak can occur when either the parasite, host, or environment, are perturbed. Myxozoan parasites are associated with a wide variety of cultured and wild fish populations. Most myxozoans are relatively benign to their vertebrate host;...
I investigated changes in plasma cortisol concentration over time in juvenile salmonids subjected to various stressors that might be encountered in their normal life cycle. This work was directed at finding a general indicator for stress in fish that could be used be used to aid fisheries research and management....
Utilizing nanocarrier based drug delivery for improving the magnitude of efficacy of chemotherapeutic agents in many diseases has acquired more attention in research applications. It has shown promising results in both preclinical and clinical trials. The Food and Drug Administration (FDA) has approved many of these polymeric carriers, and tens...
The in vitro effects of cortisol in regulating salmonid B cell functions were
investigated. B cells at three distinct stages of differentiation were examined for
cortisol sensitivity. B lymphocyte responses were examined 1) during the early stage
of the precursor, 2) during the intermediate stage of differentiation associated with
clonal...
Salmonid B lymphocytes were stimulated both in vivo and in vitro
and shown to produce antibody specific for the immunogen. A passive
hemolytic plaque assay was employed to demonstrate B cells producing
specific antibody. Characterization of plaque forming cells (PFCs)
involved sequential inhibition with a series of graded concentrations
of...
The goal of my dissertation was to explore how scale influences stream restoration prioritization strategies for an anadromous species and identify influential uncertainties that exist at different scales. My objectives were to (1) produce a comprehensive review of the Chinook salmon management challenges in California’s Central Valley and identify the...
This thesis focuses on the economic efficiency of alternative habitat, streamfiow, and land use
allocations within a major drainage of the Pacific Northwest. Specifically, productivity of present habitat
and streamfiow conditions is evaluated with respect to anadromous fish species (chinook salmon and
steelhead trout) in the John Day River Basin,...
In- stream water temperature is one of the most important environmental
factors associated with the decline in salmonid populations and their habitats in the
Pacific Northwest. Most ecological restoration practices that attempt to reduce instream
temperatures center on replanting or reestablishing riparian vegetation and
increasing flows. However, in a large...
Hyporheic zones are important regions that reside below and along the sides of streams. Within this region, several ecosystem services are provided including stream temperature regulation, habitats for a large variety of species, pollutant removal, and nutrient cycling. Exchange between the hyporheic zone and stream occurs across multiple scales, but...