Ovarian cancer, “the silent killer,” is one of the deadliest gynecological diseases due to delayed diagnosis, leading to a heavily disseminated and aggressive metastatic cancer. Therapeutic options are limited at stages III-IV of ovarian cancer, in which debulking surgery and cytotoxic chemotherapy remain the mainstays of
intervention. However, these therapeutic...
Despite advances in treatment, cancer remains among the leading causes of death in the world. Progress in the treatment of metastatic cancers was seen with chemotherapy and radiotherapy, however, the major drawbacks of conventional cancer therapies are limited efficacy and severe side effects. Magnetic fluid hyperthermia (MFH) is a new...
A continuous process for the production of ceramic materials has been studied.
This method reacted metal and oxidizer in a diffusionally controlled process,
demonstrated by reacting a magnesium particle stream and hot water vapor. Many small
rich hydrogen/air diffusion flames provide an atmosphere of hot water vapor, hydrogen,
and nitrogen...
Chinook salmon, Oncorhynchus tshawytscha, returning to the Yukon River basin and other large river systems in western Alaska have declined dramatically since the late 1990s. This continuing trend has raised concerns over the future status of the returns, and severely impacted commercial and subsistence fisheries within the drainage. Management is...
A five year longitudinal study was begun in 1976 to find a
solution to the problem of early primary children who fail in school
and then adopt the failure syndrome. The study was conducted in four
elementary schools in Oregon which had distinctly different
socio-economic populations.
The tests used for...
The physical characteristics of continental shelf waters off
Oregon during late winter and spring of 1975 are described and compared
with observations taken previously during summer. The currents
in winter are barotropic in the monthly means while in summer
the currents are baroclinic. Alongshore current fluctuations on the
time scale...
Modeling and analyzing the combined effects of disease and population dynamics
is important in understanding the effects of mechanisms such as pathogen transmission
and direct competition between host species on the distribution and abundance of different
species in an ecological community. Mathematical analysis of such models in a
spatially explicit...
Melanocytes are dendritic, pigment-producing cells located in the skin and are responsible for its protection against the deleterious effects of solar ultraviolet radiation (UVR), which include DNA damage and elevated reactive oxygen species (ROS). They do so by synthesizing photoprotective melanin pigments and distributing them to adjacent skin cells (e.g.,...