Alkylation of propylene oxide with 2-lithiofuran gave alcohol I,
which was smoothly converted to acetylfuran II. hydrogenation of II
over rhodium on charcoal followed by Jones' oxidation afforded ketone
III. Further transformation into IV was accomplished via a Wittig
reaction followed by saponification with methanolic sodium hydroxide.
Hydroboration of the...
Learning novel concepts from relational databases is an important problem with applications in several disciplines, such as data management, natural language processing, and bioinformatics. For a learning algorithm to be effective, the input data should be clean and in some desired representation. However, real-world data is usually heterogeneous – the...
Understanding the interplay between energy and water is central to effective natural resource management. With enough energy it is possible to secure sufficient water, with enough water it is possible to produce nearly boundless energy. The sun is the engine which drives the availability of both these resources; nearly every...
Latinos are the largest and most rapidly growing ethnic minority in the United States, and they have the highest dropout rates of any major ethnic group in the country (U.S. Department of Labor, 2003). Latinos' educational attainment is consistently lower than that of other students (Gandara, 2008). The majority of...
Concerns regarding maintaining wheat yield per hectare and extending
the commercial life expectancy of cultivars grown in the Yaqui
Valley of Mexico prompted this investigation. Four genetically diverse
spring wheat cultivars were grown in pure stands and in all possible
combinations at the Northwest Agricultural Research Center at Ciudad
Obregon...
Until the 1930s, flows of the Colorado River maintained approximately 781,060 hectares of wetlands in its delta. These wetlands provided important feeding and nesting grounds for resident and migratory birds as well as spawning and protection habitat for many fish and other invertebrate species. However, the Delta's wetlands started to...
The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
Reef building corals are the foundation of an entire ecosystem, but they are threatened primarily by rising ocean temperatures due to climate change. Corals depend on a thermally sensitive symbiosis with intracellular dinoflagellates. As oceans warm, this symbiosis is disrupted and results in coral mortality, declining populations and degraded reefs....