The fruitless (fru) gene in Drosophila melanogaster is a multifunctional gene having sex-specific functions in the regulation of male sexual behavior and sex-nonspecific functions affecting adult viability and external morphology. While much attention has focused on fru's sex-specific roles, little is known about its sex-nonspecific functions. The embryonic central nervous...
New ice cores retrieved from the Taylor Glacier (Antarctica) blue ice area contain ice and air spanning the Marine Isotope Stage (MIS) 5/4 transition, a period of global cooling and ice sheet expansion. Chronologies were determined for the ice and air bubbles in the new ice cores by visually matching...
Changes in the structure of the U.S. agricultural
industry since World War II have transformed it into a
highly productive component of the domestic economy. But
these changes have not occurred without indirect costs. For
example, the reliance on agricultural chemicals has produced
environmental effects causing growing concern. In addition,...
A dissertation describing the results of a series of greenhouse experiments conducted to better understand phytoremediation in stormwater bioretention systems.
Scleractinian corals, like many other cnidarians, engage in intracellular symbiosis with
dinoflagellates belonging to the genus Symbiodinium. This association makes
invaluable structural and energetic contributions to the marine environment and to the
coral reef ecosystem in particular. While many aspects of the cnidarian-dinoflagellate
relationship have been well studied, nothing is...
Intrinsically disordered proteins (IDP) are a class of proteins that lack a three-dimensional structure and their prevalence and diverse functions in the cell have only been discovered relatively recently. The intermediate chain (IC) subunit of the microtubule motor protein complex dynein contains an N-terminal disordered region, N-IC, which is central...
The within-host interactions that can occur as a result of mixed infections in wildlife likely influence the outcome of an infection. We investigated the infection frequency and outcome as well as the potential mechanisms regulating mixed infections with two Ceratonova shasta genotypes within the Chinook salmon host. Previous research in...
The objective of this study is to evaluate the potential of removing organic carbon and inorganic nitrogen contaminants, and metals from the leachate prior to any land application. New guidelines are needed to ensure the environment and our health is not put at risk. The cost of installation, operation and...
Congenital myopathies are caused by heritable mutations in particular genes. Genes mutated in congenital muscular dystrophies often encode cytoskeletal proteins, which contribute to the shape and movement of cells. We would like to know how such molecular defects lead to the muscle weakness in patients. It is therefore important to...
Pactamycin, a potent antitumor antibiotic produced by the soil bacterium Streptomycespactum, is a structurally unique aminocyclopentitol-containing natural product. Itconsists of a highly functionalized cyclopentitol core unit, two aromatic rings [3-aminoacetophenone (3AAP) and 6-methylsalicylic acid (6MSA)], and a 1,1-dimethylurea moiety. Despite its potent biological activity, the development of thisantibiotic was hampered...