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Filtering by: Creator Maier, Claudia Remove constraint Creator: Maier, Claudia Degree Level Master's Remove constraint Degree Level: Master's File Format application/pdf Remove constraint File Format: application/pdf

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  • Activation, incorporation and modification of capreomycidine during viomycin biosynthesis

    Creator:
    Fei, Xiaobo
    Abstract:
    Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. The nonproteinogenic amino acid capreomycidine is the signature residue found in the tuberactinomycin family of antitubercular peptide antibiotics and an important element of the pharmacophore. Recombinant VioG, a single module peptide synthetase from the viomycin gene cluster cloned...
    Resource Type:
    Masters Thesis
    Full Text:
    . Maier, and Dr. Rockey for their guidance and assistance throughout my graduate studies. I would like

  • Developing a system of mutagenesis in Francisella tularensis LVS

    Creator:
    Flax, Lindsay A.
    Abstract:
    Francisella tularensis is a gram-negative facultative intracellular coccobacillus that primarily infects macrophages. The causative agent of tularemia, this bacterium is considered among the most infectious organisms known, requiring fewer than ten organisms to cause disease. Although ubiquitous in nature, transmission to humans is rare but can occur via insect bites,...
    Resource Type:
    Masters Thesis
    Full Text:
    throughout the years. Special thanks to Dr. Claudia Häse for the hours spent discussing my project