Index Catalog // ScholarsArchive@OSU

Induction of autoantibodies in MRL/lpr mice exposed to 2% aniline denatured low-erucic acid rapeseed oil, an oil associated with the Spanish Toxic Oil Syndrome

Creator:: Richards, Carolyn L. K.
Abstract:: In 1981, illegal processing of rapeseed oil by a Spanish oil refinery resulted in the mass foodborne illness epidemic known as Toxic Oil Syndrome (TOS). The toxic oil associated with this epidemic was sold in neighborhood markets and by itinerant salesmen as inexpensive olive oil. Ingestion of the toxic oil...
Resource Type:: Masters Thesis

Size and surface area dependent toxicity of silver nanoparticles in zebrafish embryos (Danio rerio)

Creator:: Tuttle, George R.
Abstract:: Many studies addressing the toxicity of silver nanomaterials have found that smaller sized silver nanoparticles are usually more toxic to organisms and in cell culture than particles of larger sizes yet it is not entirely clear why. We investigated the size dependent toxicity of silver nanoparticles by measuring the response...
Resource Type:: Masters Thesis
Full Text:: ) AN ABSTRACT OF THE THESIS OF George R. Tuttle for the degree of Master of Science in Toxicology

Effects of chlorinated aliphatic hydrocarbon degradation on the metabolic enzymes in Nitrosomonas europaea

Creator:: Fawcett, Kimberly A.
Abstract:: The toxic effects of degrading the chlorinated hydrocarbons trichloroethylene (TCE), chloroform (CF) and cis-1,2-dichloroethylene (cis-1,2-DCE) were studied in the bacterium Nitrosomonas europaea. N europaea is an ammonia-oxidizing bacterium that obtains all of its energy from the oxidation of ammonia to nitrite. This metabolic process involves two enzymes, ammonia monooxygenase (AMO)...
Resource Type:: Masters Thesis
Full Text:: the degree of Masters of Science in Toxicology presented on January 12th, 1999. Title: Effects of

An in silico Approach to Determine the Influence of Surface Chemical Properties on the Toxicity of Engineered Zinc Oxide Nanoparticles

Creator:: Zhou, Zitao
Abstract:: Nanotechnology products have long since made their way to markets around the world increasing the concerns about whether nanomaterials pose a risk to our environment or health. It has been suggested that engineered nanomaterial (ENM) with broad applications and rapid commercialization need better risk assessment and regulation. However, the refinement...
Resource Type:: Masters Thesis
Full Text:: ., Toxicology Letters 1995, 79 (1–3), 45-53. 17. OECD(2012), IMPORTANT ISSUES ON RISK ASSESSMENT OF

In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

Creator:: Usenko, Crystal Y.
Abstract:: Due to their unique physical, chemical, and magnetic properties, nanomaterials have great potential for industrial development. There is a pressing need to develop rapid whole animal-based testing assays to assess the potential toxicity of engineered nanomaterials. To meet this challenge the embryonic zebrafish model was employed to determine the toxicity...
Resource Type:: Masters Thesis
Full Text:: THESIS OF Crystal Y. Usenko for the degree of Master of Science in Toxicology presented on May 29

Assessing Changes in Biological Interactions of Lipid-Coated Gold and Silver Nanoparticles Based on Physicochemical Properties

Creator:: Engstrom, Arek Mackenzie
Abstract:: Nanoparticles (NPs), particles defined by their size in a single dimension (1-100 nm), are being increasingly incorporated into commercial and industrial products due to their high surface area to volume ratio that gives them unique properties, such as optical tunability and higher reactivity than their bulk counterparts. NPs can be...
Resource Type:: Masters Thesis
Full Text:: the degree of Master of Science in Toxicology presented on May 24, 2019. Title: Assessing

Size- and Oxidation-Dependent Toxicity of Graphene Oxide Nanomaterials in Embryonic Zebrafish

Creator:: Lopez, Ryan
Abstract:: Graphene and its derivatives are two-dimensional hexagonal lattices that possess desirable physicochemical properties leading to an ever-expanding list of industrial and biomedical uses. Graphene oxides (GOs) are becoming a popular graphene alternative and while there have been human safety studies, investigations of developmental toxicity are lacking. The use of distinct...
Resource Type:: Masters Thesis
Full Text:: Ryan Lopez for the degree of Master of Science in Toxicology presented on November 2, 2021. Title

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Creator:: Norby, Tyler S.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are significant pollutants in aquatic environments. Many are carcinogenic and lead to DNA fragmentation and adduct formation in marine and freshwater organisms. Previous research demonstrates that rainbow trout (Oncorhynchus mykiss) compensate to long-term PAH dietary exposures and reduce the DNA damage. The aim of this study...
Resource Type:: Masters Thesis
Full Text:: Master of Science in Toxicology presented on June 15, 2007. Title: Antioxidant Enzyme Response in

Stability and biological responses of zinc oxide metalworking nanofluids (ZnO MWnF™)

Creator:: Niyaghi, Faraz
Abstract:: Zinc oxide nanoparticles (ZnO NPs) have demonstrated the ability to improve lubrication and thermal conductivity, and stand as promising metalworking lubricant and coolant additives due to their low cost compared to other NPs. While nanomaterials are a focus of research due to their potential to enable advanced technologies, little is...
Resource Type:: Masters Thesis
Full Text:: .............................................................................. 23 2.4 Toxicology Evaluation

Expanding the Use of 19F NMR Spectroscopy in Per- and Polyfluoroalkyl Substance Analysis: Determination of Total Fluorine and Isomeric Distribution in Aqueous Film-Forming Foams

Creator:: Schaum, Andre F.
Abstract:: Aqueous film-forming foams (AFFFs) are significant sources of per- and polyfluoroalkyl substances (PFAS) in the environment. Current analytical methods that provide quantitative measures of individual PFAS in AFFFs, such as liquid chromatography – tandem mass spectrometry (LC-MS/MS), are often complicated, time-consuming, and expensive. Methods for total fluorine analysis, though quantitative,...
Resource Type:: Masters Thesis
Full Text:: . Schaum for the degree of Master of Science in Toxicology presented on May 25, 2022. Title

ScholarsArchive@OSU

Induction of autoantibodies in MRL/lpr mice exposed to 2% aniline denatured low-erucic acid rapeseed oil, an oil associated with the Spanish Toxic Oil Syndrome

Size and surface area dependent toxicity of silver nanoparticles in zebrafish embryos (Danio rerio)

Effects of chlorinated aliphatic hydrocarbon degradation on the metabolic enzymes in Nitrosomonas europaea

An in silico Approach to Determine the Influence of Surface Chemical Properties on the Toxicity of Engineered Zinc Oxide Nanoparticles

In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

Assessing Changes in Biological Interactions of Lipid-Coated Gold and Silver Nanoparticles Based on Physicochemical Properties

Size- and Oxidation-Dependent Toxicity of Graphene Oxide Nanomaterials in Embryonic Zebrafish

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Stability and biological responses of zinc oxide metalworking nanofluids (ZnO MWnF™)

Expanding the Use of 19F NMR Spectroscopy in Per- and Polyfluoroalkyl Substance Analysis: Determination of Total Fluorine and Isomeric Distribution in Aqueous Film-Forming Foams

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