Index Catalog // ScholarsArchive@OSU

Using Mass Spectrometry to Trace Polyphenols in Human Urine

Creator:: Carrillo, Crystal V.
Abstract:: Diet History Questionnaires (DHQ) can only provide general information about a person’s nutritional intake. It is unable to cluster groups of people based on diets or lifestyles, nor identify specific foods that may play a role in disease prevention. The aim of this study was to validate the use of...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: Trace Polyphenols in Human Urine Crystal V. Carrillo1, Jaewoo Choi2, Rachel Hahn1, 2, Gerd Bobe1,2, and

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Creator:: Mans, Michael-Andres D.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are a class of contaminants ubiquitous in the environment and result from the incomplete combustion of fossil fuels. Many PAHs have been identified as procarcinogenic, and are metabolized to form DNA adducts; however, other mechanisms also may contribute to toxicity and help explain differences in toxicity...
Resource Type:: Undergraduate Thesis
Full Text:: hydrocarbons in 3D human bronchial epithelial cells By Michael-Andres Dominic Mans

Impacts of Tertiary Ligands in Catalysis in Thermostable Human Carbonic Anhydrase II by Site-directed Mutagenesis and Genetic Code Expansion

Creator:: Stevens, Danielle M.
Abstract:: Carbonic anhydrases are ubiquitous enzymes that catalyze the reverse hydration and dehydration of carbon dioxide and bicarbonate respectively. A variety of tumors in humans show overexpression of human carbonic anhydrase II (HCA II) leading to an acidic breakdown of carbon dioxide into bicarbonate. While a variety of drug inhibitors exist,...
Resource Type:: Research Paper
Full Text:: bicarbonate respectively. A variety of tumors in humans show overexpression of human carbonic anhydrase II

Meta-analysis of long-chain omega-3 polyunsaturated fatty acids and the risk of prostate cancer in prospective studies

Creator:: Chen, Sydnie J
Abstract:: Prostate cancer is the most common cancer among men in the United States. There are an estimated 115,024 incident cases so far in 2017. Risk factors for prostate cancer include age, black race, and family history of prostate cancer. In addition, healthful diet and lifestyle may affect risk of prostate...
Resource Type:: Poster
Full Text:: Sydnie Chen and Yumie Takata, PhD COLLEGE OF PUBLIC HEALTH AND HUMAN SCIENCES Background • In previous

Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay

Creator:: Luker, George W.
Abstract:: There exists a growing need to establish a better in vitro model for evaluating PAH toxicity and carcinogenicity and to improve assessments of risk to human health, especially to the complex mixtures that exist in the environment. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants due to the incomplete combustion...
Resource Type:: Undergraduate Thesis
Full Text:: of the requirements for the degree of Baccalaureate of Science in BioResource Research

Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay

Creator:: Luker, George W.
Abstract:: There exists a growing need to establish a better in vitro model for evaluating PAH toxicity and carcinogenicity and to improve assessments of risk to human health, especially to the complex mixtures that exist in the environment. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants due to the incomplete combustion...
Resource Type:: Presentation
Full Text:: ., & Douglas, G. R. (2005). Detailed review of transgenic rodent mutation assays. Mutation Research/Reviews in

Beating the curve: insulin sensitization in response to exercise

Creator:: Murphy, Michael C.
Abstract:: This paper presents a brief discussion on the phenomenon of exercise-induced insulin sensitization, including the effects of exercise on insulin-stimulated glucose uptake and potential mechanisms mediating these effects. Originally created for KIN 481 (Writing Intensive Curriculum course).
Resource Type:: Research Paper
Full Text:: critical role in the development of T2D (DeFronzo et al., 1981, 1985). This also means that improving

The Gut Microbiome Drives Benzo[a]pyrene's Impact on Zebrafish Behavioral Development

Creator:: Sieler, Michael J.
Abstract:: Benzo[a]pyrene (B[a]P) is a common environmental pollutant produced from the incomplete combustion of organic matter, such as fossil fuel emissions. In vertebrates, B[a]P exposure is associated with hyperactivity, though the underlying mechanisms driving this effect are undescribed. Mounting evidence indicates that the gut microbiome, which is the diverse community of...
Resource Type:: Undergraduate Thesis
Full Text:: of the microbiome impacts behavioral development in juvenile zebrafish. This research builds on the

Development of a method to quantitatively measure arthrogenic muscle inhibition in the peroneals

Creator:: Nelson, Whitley F., Huang, Yu-Lun, Johnson, Samuel T., and Norcross, Marc F.
Abstract:: After a joint injury, arthrogenic muscle inhibition (AMI) leads to decreased neuromuscular control and strength, as neural inhibition prevents volitional activation of the entire motor neuron pool. Traditional rehabilitation techniques such as strength training are unable to effectively reduce AMI and there is a need to identify interventions that can...
Resource Type:: Poster
Full Text:: Tape® can reduce AMI has not been established in past research. This may be due in part to previous

Combinational Effects of Retinoid-X-Receptor α (RXRα) Ablation with Oncogenic Mutations Cdk4[Superscript R24C/R24C] or N-Ras[Superscript Q61K/Q61K] after Ultraviolet Radiation Induced Melanoma Development, Combinational Effects of Retinoid-X-Receptor α (RXRα) Ablation with Oncogenic Mutations Cdk4R24C/R24C or N-RasQ61K/Q61K after Ultraviolet Radiation Induced Melanoma Development

Creator:: Sherman, Anna
Abstract:: Summary Recent research has identified Retinoid-X-Receptorα (RXRα), a nuclear receptor involved in ligand mediated transcription, as having a protective function against the malignant transformation of melanocytes after treatment with chemical carcinogens. This study used mice selectively lacking keratinocytic RXRα in combination with an oncogenic mutation, either Cdk4[Superscript R24C/R24C] or N-Ras[Superscript...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: with Oncogenic Mutations Cdk4 and N-Ras in UV Induced Melanoma Development Anna Sherman BioResource

ScholarsArchive@OSU

Using Mass Spectrometry to Trace Polyphenols in Human Urine

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Impacts of Tertiary Ligands in Catalysis in Thermostable Human Carbonic Anhydrase II by Site-directed Mutagenesis and Genetic Code Expansion

Meta-analysis of long-chain omega-3 polyunsaturated fatty acids and the risk of prostate cancer in prospective studies

Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay

Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay

Beating the curve: insulin sensitization in response to exercise

The Gut Microbiome Drives Benzo[a]pyrene's Impact on Zebrafish Behavioral Development

Development of a method to quantitatively measure arthrogenic muscle inhibition in the peroneals

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