Index Catalog // ScholarsArchive@OSU

Characterization of Selective Knockout of Thioredoxin Reductase-1 (TR1) in Mouse Melanocytes In Vivo

Creator:: Wyant, Mark B.
Abstract:: Vitiligo is a disease characterized by depigmented patches of skin. The disease is known to involve the loss of melanocytes in the basal layer of the skin in affected areas, but the underlying mechanisms are unknown. Recent evidence suggests oxidative stress and disruptions to antioxidant pathways contribute to an autoimmune...
Resource Type:: Undergraduate Thesis
Full Text:: | 15 A B Figure 1: PCR results of mouse genotyping. Schematic showing the alignment of

Enhancing Protocols to Improve Consistency Across Nanotoxicology Studies

Creator:: Luker, Sabrina R.
Abstract:: In current nanotoxicology research, there is a lack of standardization in reporting of zebrafish exposure media and sonication practices. This lack of standardization in use and reporting methods has made reproducing nanoparticle (NP) toxicity results between labs a common issue. It is important to have a standardized way of reporting...
Resource Type:: Undergraduate Thesis
Full Text:: : Stacey Harper, Environmental and Molecular Toxicology Date Andrew B. Buermeyer, Environmental

Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay

Creator:: Luker, George W.
Abstract:: There exists a growing need to establish a better in vitro model for evaluating PAH toxicity and carcinogenicity and to improve assessments of risk to human health, especially to the complex mixtures that exist in the environment. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants due to the incomplete combustion...
Resource Type:: Undergraduate Thesis
Full Text:: Molecular Toxicology Date Andrew B. Buermeyer, Environmental and Molecular Toxicology Date

The Two Wells System: A Benchmark for Monte Carlo Methods in Statistical Mechanics

Creator:: Sprueill, Henry
Abstract:: Computational statistical mechanics leans heavily on the class of Markov Chain Monte Carlo Algorithms. Many such algorithms exist, and simulations can run for several weeks, making the selection of algorithms a difficult, but critical task. In this work, we introduce a benchmark system of two quadratic wells with an analytical...
Resource Type:: Undergraduate Thesis
Full Text:: different algorithms: the replica exchange method–Parallel Tempering, flat histogram methods–1/t Wang and

Up-estuary extent and lithologic characteristics of tsunami deposits attributed to the 1700 Cascadia earthquake within Alsea Bay, OR

Creator:: Spruell, John T.
Abstract:: Cascadia’s 1700 earthquake generated a tsunami and widespread subsidence along Pacific Northwest coastline. The tsunami deposited sandy sediments in many Oregon coastal estuaries, such as Alsea Bay. Although the recurrence of subduction-generated megathrust earthquakes and tsunami events in this region are recorded in the stratigraphy, knowledge of the full inland...
Resource Type:: Undergraduate Thesis
Full Text:: Bay's position within the United States and (b) its relative position to other major estuaries along

Effects of estuary characteristics and tsunami waveforms on transported sand sheets

Creator:: Armstrong, Emma M.
Abstract:: The details of the 1700 Cascadia Subdction Zone earthquake and tsunami can be better constrained using data from tsunami sand sheets, provided knowledge of the waveform, estuary geometry and bed roughness controls on the deposition pattern of the sand sheet. In this study, we use the hydrodynamic and sediment transport...
Resource Type:: Undergraduate Thesis
Full Text:: ), 285-313. Satake, K., K. Wang, and B. F. Atwater (2003), Fault slip and seismic moment of the 1700

Towards Molybdenum Disulfide Exciton-Polaritons in Metallic Microcavities

Creator:: Embleton, Clark
Abstract:: Exciton-polaritons are a form of light-matter coupling that have potential applications as photonic transistors and logic gates. In order for a photonic transistor or logic gate to be integrated with room temperature fiber-optic technology, excitons-polaritons need to be stable at room temperature and compatible with the red and near-infrared wavelengths...
Resource Type:: Undergraduate Thesis
Full Text:: Zande’s group at the University of Illinois Urbana-Champaign. (a) (b

Gene regulatory mechanisms of the lncRNA Fendrr

Creator:: Koehler, Monika
Abstract:: Embryonic development, where organs and major structures begin to develop, requires precise coordination of numerous gene regulatory pathways. Fendrr is an long non-coding RNA (lncRNA) that plays a role in regulating gene expression in mesodermal tissues during early embryonic development in mouse. The lateral plate mesoderm (LPM) is an earlier...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: ., Horlings, H.M., Wong, D.J., Tsai, M.-C., Hung, T., Argani, P., Rinn, J.L., Wang, Y., Brzoska, P., Kong, B

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Creator:: Mans, Michael-Andres D.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are a class of contaminants ubiquitous in the environment and result from the incomplete combustion of fossil fuels. Many PAHs have been identified as procarcinogenic, and are metabolized to form DNA adducts; however, other mechanisms also may contribute to toxicity and help explain differences in toxicity...
Resource Type:: Undergraduate Thesis
Full Text:: in the DBC network. miR-320a is known to suppress tumor growth through IGF1R in NSCLC (Wang et al

Pilot study of operational parameters in microbial electrolysis cell with dark fermentation reaction

Creator:: Camplair, Mora
Abstract:: Biohydrogen production via dark fermentation (DF) and microbial electrolysis cells (MEC) demonstrate great potential for sustainable hydrogen generation. In this study, DF and MEC were coupled as a hybrid reactor and evaluated using brewery wastewater. The effect of hydraulic retention time (HRT) and buffer concentration on reactor performance were assessed...
Resource Type:: Undergraduate Thesis
Full Text:: efficiency. B. Figures Figure 8. Schematic demonstrating the bioelectrochemical mechanisms

ScholarsArchive@OSU

Characterization of Selective Knockout of Thioredoxin Reductase-1 (TR1) in Mouse Melanocytes In Vivo

Enhancing Protocols to Improve Consistency Across Nanotoxicology Studies

Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay

The Two Wells System: A Benchmark for Monte Carlo Methods in Statistical Mechanics

Up-estuary extent and lithologic characteristics of tsunami deposits attributed to the 1700 Cascadia earthquake within Alsea Bay, OR

Effects of estuary characteristics and tsunami waveforms on transported sand sheets

Towards Molybdenum Disulfide Exciton-Polaritons in Metallic Microcavities

Gene regulatory mechanisms of the lncRNA Fendrr

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Pilot study of operational parameters in microbial electrolysis cell with dark fermentation reaction

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