We have sufficient evidence that our historical management of natural resources is not sustainable. Food production is stagnating or declining. Nonrenewable energy sources on which the energy sector has historically depended are being rapidly depleted. Water resources, for which the energy and food sectors compete, are being depleted and impaired....
The natural production of methane via anaerobic digestion (AD) is facilitated by a complex community of microorganisms, primarily bacteria and archaea, referred to as the AD microbiome. AD is growing in prominence as a solution to the disposal of food waste, sewage sludge, and the organic fraction of municipal solid...
Biological invasions threaten native biodiversity, alter ecosystem function, and are a major cause of economic losses across the planet. The most impactful invaders alter disturbance regimes and initiate state shifts to outside the historical range of variability of the ecosystem. Concern for ecological and economic losses has prompted a rapid...
Global environmental change is causing local extinctions of species. When species depend on one another, as in the mutualistic relationship between plants and pollinators, loss of one interaction partner may cause cascading effects within the community – such as additional extinctions and reduced pollination services. Network theory provides a way...
Metal-oxo clusters can be described as soluble pieces of metal-oxide frameworks. Metal-oxo clusters are also the building blocks for the Metal-Organic Frameworks (MOFs) and coordination polymers. A better knowledge of metal-oxo clusters helps fundamentally understand geosciences, molecular engineering, catalysis, single-molecule magnetism, and MOFs for synthesis, design, and modification of these...
Most marine fishes experience high rates of mortality during their early life history stages with far reaching consequences for adult population dynamics. Within a few weeks of hatching, relatively small changes in larval growth and mortality rates can lead to orders of magnitude variability in year-class strength. Growth and survival...
As one of the most popular data types, the point cloud is widely used in various appli- cations, including computer vision, computer graphics and robotics. The capability to directly measure 3D point clouds is invaluable in those applications as depth information could remove a lot of the segmentation ambiguities in...
This dissertation consists of two qualitative grounded theory studies on the professional development process experienced by first year high school counselors during the United States’ 2020 public health and sociopolitical crises. Chapter two contains the first study which answers the research question: What is the professional development process experienced by...
In high volume automated discrete item batch production systems, the batches or lots are typically fixed quantity (i.e., size), with setups incurred between the different production lots. Processing times for the fixed-size lots are relatively constant when the workstation is operating however, random workstation disruptions cause variability in the lot...
Continuous Improvement (CI) of academic computing programs is a main requirement of accreditation. Academic computing programs must have a well-documented CI plan in order to be granted accreditation. Based on the existing literature, we developed a comprehensive CI (or 360-CI) model consisting of 8 components: course, curriculum, administration, faculty, research,...
In this dissertation, I present experimental observations of multiply charged atomic ions (MCAI) generated from interactions of atomic/molecular clusters with moderately intense nanosecond laser pulses. This process is also known as Coulomb explosion (CE) and it has been extensively studied in intense laser fields using ultrashort pulses. Several prevailing theories...
Deeply weathered soils in tropical rainforests and savannas are classified as Ferralsols according to the World References Bases for Soil Resources (WRB). Ferralsols are most nearly akin to the Oxisols order defined in the US Soil Taxonomy. The acidity, low cation exchange capacity, and strong phosphorus retention by the oxidic...
Nonalcoholic fatty liver disease (NAFLD) is characterized by an accumulation of neutral lipids in the form of triglycerides and cholesterol esters accounting for >5% of liver weight. Excess neutral lipids accumulate in large lipid droplets, i.e., macrosteatosis, displacing the nucleus of cells. Current theory suggests neutral lipid accumulation is the...
In this dissertation, we consider two problems in number theory, both relating to modular forms. First we consider when a given modular form can be expressed as a quotient in Dedekind's $\eta$ function. Rouse and Webb \cite{RW} have determined the integers $N \leq 500$ such that the graded ring of...
Students with disabilities are not being afforded the same access to sporting opportunities as their peers without disabilities. The purpose of this dissertation was to build on a foundation of information regarding collegiate adaptive sports through a Critical Disabilities Studies lens. Specific aims included: (1) identifying and describing intercollegiate, adaptive...
This thesis builds on a modeling tool that has been developed to link thermodynamic modeling and concrete performance. This tool is intended to predict the performance for modern concrete mixtures made with ordinary portland cement (OPC), conventional and novel supplementary cementitious materials (SCMs), and limestone (Ls). The first part of...
Ethical and training standards across counseling-related professions contain competencies related to race and ethnicity as necessary research and practice components. One such counseling-related sub-specialty is Play Therapy, which acknowledges that professionals utilizing play therapy techniques must consider racial and cultural context, trauma, and intersectionality when working with children. However, there...
Arctic warming is exposing thawing permafrost to repeated freeze-thaw, a disruptive process that can alter soil biogeochemistry and physical structure. To investigate the impact of permafrost exposure to freeze-thaw, soil response was tested across three scales: 2.5 cm³ aggregates, a forested hillslope, and two sites at contrasting latitudes. XCT imaging...
Climate change presents multiple stressors that are impacting marine life. As carbon dioxide emissions continue to increase in the atmosphere, atmospheric and sea water temperatures increase. In addition, more carbon dioxide is absorbed into the oceans, reducing pH and aragonite saturation state, resulting in ocean acidification (OA). Tightly coupled with...
The distribution of mobile marine predators often reflects underlying dynamic ecological processes. The geographical focus of this PhD is the South Taranaki Bight (STB) of New Zealand, where wind-driven coastal upwelling generates productivity and prey to support a blue whale foraging ground. The STB is also New Zealand’s most industrial...
Assessing AI systems is difficult. Humans rely on AI systems in increasing ways, both visible and invisible, meaning a variety of stakeholders need a variety of assessment tools (e.g., a professional auditor, a developer, and an end user all have different needs). We posit that it is possible to provide...
Exposure assessment is necessary to determine the frequency and magnitude of environmental contaminants, especially since exposure may lead to adverse health outcomes. Traditional personal exposure assessment tools such as biological samples are limited in their ability to capture a wide range of chemical exposures from a single sample, and others...
The imposing andesite stratovolcano is the characteristic expression of subduction zone magmatism, posing hazards to coastal populations and bearing insight into deep Earth processes. On a map of a typical volcanic arc, one can easily distinguish the approximately linear alignment and regular spacing of these major edifices that stand out...
The recent advent of large-scale microbiome studies enabled by high-throughput sequencing calls for innovative statistical methodologies that are capable of tackling a myriad of challenges presented by microbiome data. Compelled by this need, we focus on the development of statistical tools for two types of problems that arise in microbiome...
Desalination stands for removing salt from saline water, and produce freshwater. Desalination technologies have been envisioned as a potential solution for freshwater production from oceans as an immense source of water acquiring 97% earth’s water, and 75% of earth’s surface. However, one third of world’s population face water scarcity every...
Within this dissertation, we develop tools and techniques to demonstrate the feasibility of real-time optimization of a magnetohydrodynamics generator. To ease computational complexity, we work on the kinematic magnetohydrodynamic system, prescribing the fluid-flow and model the material response of the system through an updated Generalized Ohm’s law. We focus on...
Due to a growing body of literature documenting declines in pollinator populations, there has been increased public interest in pollinator conservation. In urban and suburban landscapes, many gardeners and urban land managers are interested in gardening for pollinators, particularly bees. Simultaneously, many homeowners and municipalities are interested in other aspects...
Multiple hypothesis testing has been a popular topic in statistical research. Although vast works have been done, controlling the false discoveries remains a challenging task when the corresponding test statistics are dependent. Various methods have been proposed to estimate the false discovery proportion (FDP) under arbitrary dependence among the test...
Substituted phenols are important substructures for pharmaceuticals, agrochemicals, natural products and biological probe molecules. The properties of phenolic molecules are substantially influenced by the substitution patterns of the phenolic ring. The chemical synthesis of phenols with various substitution patterns is an enduring challenge and multiple strategies have emerged. However, some...
This work – in which three peer-reviewed academic papers are presented – addresses the ap-plication of Bayesian Reinforcement Learning to the control of a class of ocean wave energy conversion systems. The first paper presents a comparison of a Reinforcement-Learning (RL) based wave energy converter controller against standard Reactive Damping...
Plant-pollinator mutualisms are one of the most prevalent and economically important mutualisms in nature. Like many other ecological systems, plant-pollinator communities are threatened by anthropogenic activity, both directly (e.g., habitat conversion and fragmentation) and indirectly (e.g., climate change). While we are aware of many of the activities that adversely impact...
Multiple wave energy converter (WEC) archetypes exist with varying power take-off (PTO) designs in the attempt to maximize ocean energy harnessed and converted into useful energy. The pendulum PTO is popular for its simple, yet robust functionality due to its internally located components and simple operation. Additionally, this PTO does...
Restoration programs effectively prevent or mitigate wildfires and pest outbreaks in the forest lands. The most common approach is to selectively harvest smaller and dead trees in order to preserve larger and superior trees. Ponderosa pine, Pinus ponderosa, (PP) lumber is one of the common species harvested from restoration programs...
In 2017, the Rohingya refugee crisis became recognized as the fastest growing and among the densest concentration of refugees in the world. The Rohingya have no legal citizenship in any country and are considered a stateless population. Pregnant persons and children are often more vulnerable to the effects of humanitarian...
Domestic violence (DV) is a major social and public health issue in countries such as India and Pakistan where patriarchy is the way of life and cultural norms, and beliefs hold a greater say in community decision-making. Women in these countries are discriminated against from birth and face hurdles in...
Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
Climate change will impact the location of suitable habitat for tree species in the Pacific Northwest. Locations that become unsuitable will experience increased levels of tree mortality and diminished levels of tree growth. Understanding how these impacts will spatially manifest is vital for efficient management of natural resources. An invaluable...
The energy harvesting performance of oscillating airfoils is studied using a discrete vortex model (DVM) with a leading-edge separation criterion. The airfoil undergoes a combined sinusoidal heaving and pitching motion at reduced frequencies of k = 0.06 − 0.16, with heaving amplitude of h0 = 0.5c, and pitching amplitude of...
Manufacturing technology has continuously evolved and advanced over the past century; this has led to an increase in the production of consumer and industrial goods driven by simultaneous growth in population and wealth. Despite the resulting economic and labor growth, environmental impacts of manufacturing have increased dramatically due to the...
Exergy relates to thermodynamic value or usefulness in the universe. In this dissertation, three methods in the realm of "process intensification" are explored to reduce exergy destruction by equipment and processes that are used to convert and upgrade methane. Thermodynamic efficiency of a virtual heat exchanger is improved with a...
Interactions and feedbacks among climate change effects and continued human impacts will exacerbate impacts to water resources in complex ways. An urgent imperative of the hydrologic community is to understand the response of hydrologic systems to these perturbations, thus contributing to long-term sustainability of water resources in an uncertain future....
With growing interest in mass timber, especially mass timber panels (MTP), there has been a need to better understand their structural properties. One of the most versatile uses for MTP are as floor systems. Under new code provisions, these floors can be utilized in new and taller building types, but...
Near-surface advanced argillic hydrothermal alteration zones, also referred to as lithocaps, are characterized by quartz, alunite, clays (pyrophyllite and kaolinite group minerals), and minor F-bearing aluminosilicates (i.e., topaz, zunyite, diaspore, and APS) that form where water-, SO2-, and HF-rich gas condenses into shallow groundwater, acidifies, and reacts with rocks. The...
Intimate partner violence (IPV) against American Indian/Alaska Native (AIAN) women is a significant public health issue, requiring deeper understanding on how to better support Native women survivors. This mixed-methods project utilizes both quantitative and qualitative methods to examine factors associated with support-seeking behaviors and explore how women seek support and...
The presence of per- and polyfluoroalkyl substances (PFAS), organic contaminants first synthesized in the 1940s, has been reported worldwide in a variety of environmental matrices and ultimately in biological systems including humans. Ongoing research into PFAS has included identifying novel PFAS, assessing their fate and transport in the environment, and...
Climate change has the potential to accelerate many forms of human migration and mobility, yet almost all of the key migration outcomes of interest are determined predominantly by governance, or the norms, laws, and institutions involved in the coordination of human society. These outcomes include the decision whether or not...
Melanocytes are dendritic, pigment-producing cells located in the skin and are responsible for its protection against the deleterious effects of solar ultraviolet radiation (UVR), which include DNA damage and elevated reactive oxygen species (ROS). They do so by synthesizing photoprotective melanin pigments and distributing them to adjacent skin cells (e.g.,...
Pile caps are structural elements used to transfer loads from columns to a group of piles, which transfer them to stronger soil layers. Pile cap with horizontal distance between the column and piles less than twice its effective depth is categorized as "deep," where significant nonlinear strain distribution occurs through...
Counselor education programs traditionally have student counselors role-play therapy sessions to enhance skills in rapport building, aligning with a theoretical orientation, and other essential communication skills. Students, however, are often left to determine their own choice of words when engaging in these practice sessions, and consequently, experience uncertainty regarding how...
In order to mitigate climate change and increase sustainability, many states and nations have introduced policies intended to support the growth of renewable energy sources. Among these sources, wind energy has risen most prominently in the 21st century. However, its rise has been accompanied by various constraints and by local...
Polycyclic aromatic hydrocarbons (PAHs) are complex mixtures that form when organic matter is burned. Humans are primarily exposed to PAHs via air pollution from incomplete combustion of fossil fuels and biomass, such a motor vehicle exhaust, cigarette smoke, wood smoke, or industrial emissions; or via ingestion of PAHs bound to...
Critical Infrastructures (CIs) such as energy, water supply, telecommunications, and transportation are highly vulnerable to cascading failures due to their interdependent operations. A resilient network is crucial to withstand the impact of functionality loss in disruptive events. This research evaluates network expansion as a proactive resilience strategy in which new...
The South Pole ice core (SPC14), drilled in the field seasons of 2014/2015 and 2015/2016, is an intermediate length, 1,751-m ice core which preserves a 54,000-year record of past climate and atmospheric composition. The SPC14 ice core adds to the spatial grid of ice cores in Antarctica extending into the...
Variations in ocean conditions influenced by climate fluctuations may impact fish populations by changing their spatial distribution, physiology, survival, and other ecological features. Somatic growth is a crucial aspect of the biology of fishes and an important contributor to biomass fluctuations. Climate variability also affects somatic growth rates along the...
Health anxiety prevalence is increasing (Tyrer et al., 2019). Health anxiety is a preoccupation or overestimation of the serious physiological symptoms that cause significant distress (Salkovskis & Warwick, 2001). Those with health anxiety may endure significant suffering, intense misery, and for some health anxiety leads to suicide (Tyrer & Tyrer...
In this study, I investigate how target value uncertainty may lead to acquirer mispricing of an acquisition target and how the mispricing may be a determinant of goodwill impairment. To the extent the mispricing leads to both high and low industry-adjusted purchase price multiples (PPMs are my proxies for overpayment...
Establishing a therapeutic alliance or a therapeutic bond has long been seen as an essential component of obtaining positive treatment outcomes in clinical practice. More recently, the idea of recognizing therapeutic alliance ruptures (disagreements about the tasks or goals of therapy or a problem in the therapeutic bond) during counseling...
A molecular approach to metal oxides allows to the study to fundamental bonding and formation behavior for such metals. Moreover, the molecular nature of such oxides or metal-oxo clusters allows the possibility of exploitation of the properties of the parent oxides. The tetravalent metals, in specific, (M=Zr, Hf, Ce, Th,...
Wheat sharp eyespot (SES), caused by the soil-borne fungus Rhizoctonia cerealis is a common stem disease of wheat globally. The disease caused a severe and extensive epidemic throughout the Willamette Valley of Oregon in 2014 and has remained one of the most important wheat diseases in this region. However, litte...
Sensing is a significant engineering science which quantify parameters from the physical world and discover the physics running behind the measurement process. Optical sensing makes use of electromagnetic waves from infrared to ultraviolet on the light spectrum as a medium to measure variables, such as position, temperature and strain. Image...
Sudden oak death is caused by the clonally reproducing generalist oomycete Phytophthora ramorum. The pathogen can infect more than 130 different plant hosts including Quercus spp., Larix kaempferi, and Notholithocarpus densiflorus, as well as common nursery genera such as Rhododendron and Camelia, where it causes symptoms ranging from bleeding cankers...
The demand for the development of sustainable energy is an all time high as we burn through limited fossil fuel reserves and as environmental concerns rise every year. Renewable energy sources such as wind and solar power have limitations due to inconsistent power supply that cannot meet the regular needs...
In this dissertation, I describe the experimental investigation of electron diffraction of neutral and ionic clusters doped into superfluid helium droplets. The project is aimed at contributing to the development of an overall approach called ‘serial single molecule electron diffraction imaging (ss-EDI), a potential approach to solve macromolecule structures bypassing...
Covering half of South America, Brazil is one of the largest agricultural and commercial forest producers globally, with a correspondingly complex road network necessary to support the production and marketing processes of such goods. Contrary to global statistics, almost 90% of the country’s road network is classified as unsealed or...
Organic semiconductors have attracted considerable attention due to their applications in low-cost, solution-processable (opto)electronic devices. An important class of high-performance organic semiconductors is pentacene derivatives, which exhibit high charger carrier mobilities in field-effect transistors and ultrafast singlet fission in photovoltaic devices. These derivatives have served as benchmark materials for systematic...
Taking long-term electrical measurements of a large number of neurons simultaneously is required for many modern neuroscience experiments. However, such experiments are currently limited by the shortcomings of traditional neurosensing technology. For example, there is a significant mechanical mismatch between rigid silicon probes and soft biological tissues. This mismatch can...
In computer science, learning abstract fundamental programming concepts requiring students to understand memory management can be very difficult and lead to misunderstandings that carry on into advanced topics. This is especially true in data structures with abstract data types. Understanding how novice students think and reason about data structures is...
The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
The primary goal of this dissertation is to improve the quality of nuclear data available to the nuclear science community. We propose to accomplish this by applying machine learning algorithms to the large number of available benchmark experiments and simulations, with the goal of determining which nuclear data have strong...
Animals aggregate and interact in nonuniform and nonrandom patterns, which lead to group level characteristics that have important evolutionary and ecological consequences. Network analysis provides a useful conceptual framework for linking animal interactions at all scales from dyads to communities, to populations and ecosystems. Despite exciting theoretical and applied advances...
Characterizing stakeholder behavior when making decisions in watershed management is a great challenge for planners, not only because plans are associated with physical uncertainties but also because stakeholders’ behaviors are influenced by numerous factors. Since stakeholders’ decision-making is linked to multiple types of uncertainty, communication of uncertainty to stakeholders by...
Pseudoloma neurophilia is the most common pathogen reported in zebrafish (Danio rerio) research facilities and is an important threat to the zebrafish model. This microsporidian parasite can cause clinical disease, but more importantly is a causative agent of non-protocol induced variation in research. Studies utilizing infected zebrafish, could potentially confound...
The continuous improvement of construction operations requires a systematic approach of monitoring and making appropriate control actions. However, the lack of real-time information hinders this workflow and eventually compromises timely and effective decision-making. Project managers spend a great deal of time and effort to solve problems emerging from lack of...
The early care and education workforce, including those who work in center- and home-based child care (HBCC) settings, is situated within outside systems of child care supports and resources. Some outside system components serve to support compliance with regulatory guidelines (e.g., child care licensing: health and safety protocols, minimum training...
We present a method for deterministically solving the consistent temperature and frequency dependent phonon radiative transport problem. We use the single relaxation time (SRT) approximation in the Self-Adjoint Angular Flux (SAAF) form with discrete ordinates (S_N) angular discretization method and continuous finite element method (CFEM) for spatial discretization. Included are...
Wind turbines serve an increasing proportion of total energy generation, with expanded onshore and offshore installations proceeding worldwide. Continued construction, expansion, and operation of wind energy installations must be managed in conjunction with effects on local and migratory wildlife, specifically bird and bat species that may be affected by wind...
Autonomous agents that sense, decide, act, and coordinate effectively with each other are critical in many real-world domains such as autonomous driving, search and rescue missions, air traffic management, and underwater or deep space exploration. All such domains share a key difficulty: though high-level mission goals are clear to system...
Despite near unanimous opinion on the consequences of climate change by scientific community, the rate at which carbon is emitted into the atmosphere continues to increase. The need for a clean and sustainable source of energy is therefore one of humankind's most urgent challenges. Solar energy is the most abundant...
The increase in the demand for energy is estimated to be 28 TW by a year of 2050, which is twice of the energy produced in 2010, in response to the unprecedented growth of the global population. Current energy market is heavily relying on the fossil fuel, which brings the...
The production of carbon and export to deep ocean sediments is linked to carbon partitioning between the ocean and atmosphere and is a key driver of climate change over the glacial-interglacial transition. Yet conflicting reconstructions create barriers to understanding changes to the carbon system over this important climate transition. Production...
We live on an Urban Planet. The current unprecedented urbanization is accompanied by intensive land cover transition and demographic shifts from rural to urban livelihoods. Cities serve as cultural, economic, political centers that facilitate wealth creation and innovation of the society, sustaining human from multi-dimensions with large ecological footprints far...
The grand plan of carbon neutralization and COP26 in Glasgow require a quick shift of energy sources from conventional fossil fuel to a more renewable substitute such as wind, or solar energy. However, the intermittency of those renewable energy sources does not meet the demand of the energy, which requires...
Home-based counseling (HBC) occurs when counselors provide therapy services to individuals and families within the clients’ home environment. Since its inception in the 1980s, HBC has become a common practice within the counseling field. In 2014, the U.S. Bureau of Labor Statistics (2014) named HBC one of the fastest-growing divisions...
This study explores how multispecies social networks influence small farmers' perceptions of and responses to climate change across Oregon. Local food sovereignty and food system resilience depend on a robust local food system in which small farms play a critical role. To maintain their viability, small farmers must adapt to...
Stony corals are the ecosystem engineers of the vital, dynamic, and complex marine ecosystem known as coral reefs. Globally, coral reefs are undergoing degradation from multiple anthropogenic stressors. Coral reef organism holobionts, or the host along with its microbial components, are key to reef ecosystem success and functioning. Marine microbes...
Phytoplankton initiate the marine carbon cycle by fixing carbon dioxide into biologically available compounds. These abundant single celled organisms mediate carbon flux from the atmosphere to the deep ocean and are the base of the marine food web, supplying new carbon to higher trophic levels. Phytoplankton are highly diverse and...
Understanding the spiritual worldview of clients is a core element of multicultural competency for mental health professionals. One spiritual and religious population is members of The Church of Jesus Christ of Latter-day Saints and related Latter-day Saint populations. The Book of Mormon is an important sacred text of this population....
In areas such as spatial analysis and time series analysis, it is essential to understand and quantify spatial or temporal heterogeneity. In this dissertation, we focus on a spatially varying coefficient model, in which spatial heterogeneity is accommodated by allowing the regression coefficients to vary in a given spatial domain....
There is a national interest in improving the quality of science, technology, engineering, and mathematics (STEM) education in institutions of higher education in the face of mounting difficulties. Reports by the National Academy of Sciences in 2018 and 2020 found that the dissemination and adoption of effective, timely change initiatives...
The rapid pace of climate change is increasing tree mortality and highlighting the need to improve the mechanistic understanding of plant function under increased water stress. However, the processes that control soil moisture availability in steep mountainous terrain are poorly understood, as are the relative effects of atmospheric and soil...
The coastal region is home to many types of surface fronts that exist on a submesoscale (1-10 $km$). While in situ observations capture point or transect observations of frontal behavior subsurface, their complex spatial patterns can be well-captured using remote sensing techniques, which provide synoptic views of the ocean surface...
In this dissertation, we derive and implement a new transport-diffusion hybrid algorithm for solving thermal radiative transfer (TRT) problems. Using the method of nonlinear elimination (NLEM), the TRT system of equations can be written in terms of a transport equation with the absence of scattering and a diffusion equation. The...
Deep learning has recently revolutionized robot perception in many canonical robotic applications, such as autonomous driving. However, a similar transformation has yet to occur in more harsh environments including underwater and underground. This is due in part to the difficulty in deploying robots in these environments, which lack large real...
Modern sensors are complex systems comprising multiple sub-systems such as transducers, analog and mixed-signal interface circuits, digital processing circuits, and packaging. Over the last few decades, innovations in these sub-systems combined with their increased integration in complementary metal-oxide semiconductor (CMOS) processes have led to the rapid growth in sensors for...
The Hippo signaling pathway is an evolutionarily conserved regulator of cell growth, proliferation, and apoptosis. A key function of the pathway is to regulate the subcellular distribution and activity of Yorkie in Drosophila or Yes-associated protein (YAP) and transcription co-activator with PDZ-binding motif (TAZ) in mammals. The dysregulation of the...
In biology, function and disease are closely intertwined, requiring the coordination of hundreds of intricate chemical reactions. Interdisciplinary cooperation between chemical and biological approaches is necessary to decipher the chemical links between physiological and pathological conditions. In this arena, the precision tools made possible with chemical biology can manipulate and...
Climate change impacts everyone’s food and water security. Increasing global temperatures accelerate the hydrologic cycle and consequently impact the water resources for billions of people worldwide. Countless models have been developed to represent various components of the hydrologic cycle at various spatial and temporal scales. These are often validated against...
There has been tremendous growth in using data analytic and machine learning algorithms to make critical decisions, such as in the national power grid, healthcare operations, and autonomous vehicles. Employing data analytic for decision-making allows cyber attackers to manipulate the decisions of these algorithms through data falsification. Hence, the trustworthiness...
Kelps are large brown algae in the order Laminariales and are foundation species that form the basis of kelp forests. Present across a quarter of the world’s coastlines, kelp forests provide diverse services to coastal communities, as habitat for commercially and culturally important species, as a food source for humans...
Cherenkov detectors have been developed and used in several fields since the discovery of Cherenkov radiation. They do have several advantages compared with other detector types, such as low noise due to the low-energy threshold of Cherenkov radiation, and short decay constant (on the order of picoseconds). However, the light...