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Filtering by: Alternative title ssim 04-60-10 Remove constraint Alternative title ssim: 04-60-10 Degree Name Doctor of Philosophy (Ph.D.) Remove constraint Degree Name: Doctor of Philosophy (Ph.D.) Non-Academic Affiliation Linus Pauling Institute Remove constraint Non-Academic Affiliation: Linus Pauling Institute

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  • Brassicas, microbes, and metabolites : a multi-omic investigation of cruciferous vegetable phytochemical metabolism

    Creator:
    Bouranis, John A.
    Abstract:
    Phytochemicals from cruciferous vegetables, such as broccoli, contain a multitude of bioactive compounds that prevent and suppress cancer and promote optimal health. Some of the health promoting effects of cruciferous vegetables are attributed to a class of compounds known as isothiocyanates (ITCs), a potent nuclear factor erythroid 2–related factor 2...
    Resource Type:
    Dissertation
    Full Text:
    Broc and NC Samples..60 Figure S2.3 Spearman’s Correlations Between Family Abundance and SFN-NIT and

  • The Role of Cellular Senescence in the Development of Alzheimer's Disease

    Creator:
    Riordan, Ruben
    Abstract:
    Alzheimer’s Disease (AD) is a neurodegenerative pathology currently affecting nearly 44 million individuals worldwide, yet there are not currently any effective treatments or preventions for AD despite the rapid development in our understanding of the disease over the last four decades. The medical and sanitary innovations of the last century...
    Resource Type:
    Dissertation
    Full Text:
    senescence. This indicates that of our five models, only the two tau-based mouse models (P301S at 10 moths

  • Characterization of the Mechanisms of Action and Molecular Targets of Hop-derived Flavonoids in the Mitigation of Obesity-related Metabolic Impairments

    Creator:
    Paraiso, Ines L.
    Abstract:
    Obesity is a complex multifactorial disease resulting from excessive energy intake compared to energy expenditure. The excess energy is mostly stored as fat in enlarged adipocytes, but some lipids may infiltrate other organs such as the liver to form ectopic fat. Adipose tissue and ectopic fat produce and secrete a...
    Resource Type:
    Dissertation
    Full Text:
    methods………………………………………………………………..60 Results…………………………………………………………………………….….65 Discussion

  • Investigation of Procyanidins Used in Botanical Dietary Supplements

    Creator:
    Rue, Emily A.
    Abstract:
    Polyphenolic compounds found in foods such as fruits, vegetables, legumes, nuts and grains, are an integral part of the human diet. Within polyphenols, proanthocyanidins are referred to as condensed tannins and encompass procyanidins, propelargonidins and prodelphinidins. Among these, procyanidins are the largest group. Recent interest in these compounds is related...
    Resource Type:
    Dissertation
    Full Text:
    .................................................................................................. 60 3.4.1 Negative ion fragmentation pathways of procyanidins ........... 60 3.4.2 Sequencing