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Filtering by: Alternative title ssim Report no. 1704 Degree Name Doctor of Philosophy (Ph.D.) Non-Academic Affiliation Linus Pauling Institute

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Creator:

Riordan, Ruben

Abstract:

Alzheimer’s Disease (AD) is a neurodegenerative pathology currently affecting nearly 44 million individuals worldwide, yet there are not currently any effective treatments or preventions for AD despite the rapid development in our understanding of the disease over the last four decades. The medical and sanitary innovations of the last century...

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Dissertation

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of AD. However, not every model is guaranteed to develop cellular senescence, and previously no
Characterization of the Mechanisms of Action and Molecular Targets of Hop-derived Flavonoids in the Mitigation of Obesity-related Metabolic Impairments

Creator:

Paraiso, Ines L.

Abstract:

Obesity is a complex multifactorial disease resulting from excessive energy intake compared to energy expenditure. The excess energy is mostly stored as fat in enlarged adipocytes, but some lipids may infiltrate other organs such as the liver to form ectopic fat. Adipose tissue and ectopic fat produce and secrete a...

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Dissertation

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‐mediated mechanism while investigating its anti carcinogenic properties. This report found that XN
Brassicas, microbes, and metabolites : a multi-omic investigation of cruciferous vegetable phytochemical metabolism

Creator:

Bouranis, John A.

Abstract:

Phytochemicals from cruciferous vegetables, such as broccoli, contain a multitude of bioactive compounds that prevent and suppress cancer and promote optimal health. Some of the health promoting effects of cruciferous vegetables are attributed to a class of compounds known as isothiocyanates (ITCs), a potent nuclear factor erythroid 2–related factor 2...

Resource Type:

Dissertation

Full Text:

by the gut microbiome or it can be directly excreted with no biological activity (Figure 1.1) (92

ScholarsArchive@OSU

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Characterization of the Mechanisms of Action and Molecular Targets of Hop-derived Flavonoids in the Mitigation of Obesity-related Metabolic Impairments

Brassicas, microbes, and metabolites : a multi-omic investigation of cruciferous vegetable phytochemical metabolism

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