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Filtering by: Advisor Christensen, John M. Remove constraint Advisor: Christensen, John M. Degree Name Doctor of Philosophy (Ph.D.) Remove constraint Degree Name: Doctor of Philosophy (Ph.D.) Non-Academic Affiliation Oregon State University. Graduate School Remove constraint Non-Academic Affiliation: Oregon State University. Graduate School

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Evaluation of solid dispersed particles for formulation of oral ibuprofen tablets

Creator:

Sartnurak, Soisurin

Abstract:

Dissolution profiles of two commercial products (Motrine and Rufen®) were analyzed and compared at 8 pH levels, ranging from pH 2.0 to pH 8.0. It was demonstrated, as expected, that the rate and extent of ibuprofen dissolution dissolution was pH dependent. In vitro dissolution characteristics of the ibuprofen solid dispersion...

Resource Type:

Dissertation

Full Text:

Formulation of Oral Ibuprofen Tablets Abstract approved: L. -,, , ..,-...--- John M. Christensen, Ph.D
Product formulation of phenylbutazone, theophylline, tolbutamide and pharmacokinetics-toxicities of theophylline injections in pigs

Creator:

Suvanakoot, Uthai

Abstract:

A two-part study was conducted with three poorly water soluble drugs (phenylbutazone, tolbutamide, theophylline) to develop two new drug delivery systems based on physical-chemical approaches. In the first part, tolbutamide and phenylbutazone were made into solid dispersions with various excipients using a lyophilization technique. In vitro dissolution studies of these...

Resource Type:

Dissertation

Full Text:

Chulalongkorn University for full financial support throughout my study, and to Dr. John M. Christensen and Dr
Development of novel oral enteric-coated aquaculture vibrio vaccines

Creator:

Wong, George Kaon

Abstract:

An oral Vibrio vaccine for salmonids was developed. The vaccine was produced by spray coating lyophilized formalin-killed whole cells of Vibrio anguillarum (VA LS 1- 74) onto non-pareil sugar beads. Then methacrylic acrylic acid copolymer (Eudragit L-30D) was applied as an enteric protective coating. Using x-ray radiographic techniques, it was...

Resource Type:

Dissertation

Full Text:

Aquaculture Vibrio Vaccines Abstract approved: 114edaatecr 4for Privacy ohn M. Christensen, Ph.D. An oral
Analysis of nonlinear pharmacokinetic systems and the nonlinear disposition of phenylbutazone in equine (horses)

Creator:

Ma, Lian

Abstract:

The first part of the dissertation is to evaluate the use of proposed and established equations for area under the plasma concentration versus time (AUC) for molecules undergoing nonlinear Michaelis–Menten pharmacokinetic elimination. The effects of varying Michaelis-Menten parameters, rate of drug absorption, or bioavailability on the predictability of drug exposure...

Resource Type:

Dissertation

Full Text:

: John Mark Christensen The first part of the dissertation is to evaluate the use of proposed and
Disposition of C H N O S in rats and three antiulcer agents in llamas

Creator:

Limsakun, Tharin

Resource Type:

Dissertation

Full Text:

Llamas Abstract approved: John Mark Christensen, Ph.D. The solubility and disposition of a new
Fish oral antigen delivery system development and optimization

Creator:

Zhang, Jia Ai (Allen)

Abstract:

Oral administration is the most practical way of vaccination of fish. It has advantages over intraperitoneal injection and immersion methods that include no stressful handling, no interference with routine fish husbandry and antigens can be delivered to the fish in their feed. An oral antigen delivery system was developed for...

Resource Type:

Dissertation

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Optimization Abstract Approved: John Mark Christensen, Ph.D. Oral administration is the most practical
Pharmacokinetics of ampicillin, gentamicin, amikacin, and omeprazole in llamas

Creator:

Kasiwong, Srirat

Resource Type:

Dissertation

Full Text:

, Amikacin and Omeprazole in Llamas. Abstract approved: John Mark Christensen Ampicillin sodium and
1) Preparation of Acetaminophen Capsules Containing Beads Prepared by Hot-melt Direct Blend Coating Method 2) Pharmacokinetic Modeling and Monte Carlo Simulations in The Context of Additional Criteria for Bioequivalence Assessments 3) Pharmacokinetic Prediction of Levofloxacin Accumulation in Tissue and its Association to Tendinopathy

Creator:

Pham, Loan

Abstract:

The thrust of this thesis is to study oral solid dosage formulation using hot melt coating method and to use pharmacokinetic modeling and simulation (PK M&S) as a tool that can help to predict pharmacokinetics of a drug in human and the probability of passing various bioequivalence criteria of the...

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Dissertation

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Tendinopathy. Abstract approved: John M. Christensen The thrust of
Examining Agricultural Household Welfare through Output Marketing Choices and Land Market Efficiency : Evidence from Rural India

Creator:

Dickson, Caleb

Abstract:

Development research and policy aim to improve household welfare by improving access to assets and economic opportunities (Besley & Burgess 2000; Deininger et al. 2003). In rural and agrarian contexts, these goals may be achieved by well-functioning markets for outputs, inputs, off-farm work, and credit. The status of these markets...

Resource Type:

Dissertation

Full Text:

: ___________________________________________________ John M. Antle Development research and policy aim to improve household welfare by
Outcome Distributions in Impact Assessment : Climate Change and Technology Adoption in Pacific Northwest Agriculture

Creator:

Zhang, Hongliang

Abstract:

Increased temperature and precipitation variability and frequent extreme weather events due to climate change pose a threat to farming operations and agricultural communities. The recent IPCC assessment shows that the projected climate change will, on average, reduce wheat yields by 5% in temperate regions without adaptation and even more if...

Resource Type:

Dissertation

Full Text:

: _____________________________________________________ John M. Antle Increased temperature and precipitation variability and frequent extreme weather

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Academic Affiliation

School of Education12
College of Pharmacy8
College of Health and Human Performance6
Applied Economics2
Crop and Soil Science1
more Academic Affiliations »

Advisor

Dunn, John M.19
Christensen, John Mark5
Christensen, John M.3
Antle, John M.2
Hart, John M.1
more Advisors »

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 1982 to 2017

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Committee Member

McCubbin, Jeff3
Anderson, Gordon W.2
Boarman, Marie2
Brodsky, Meredith2
Dickinson, Vern2
more Committee Members »

Creator

Hsu, Pao Yin2
Ahn, Byoungchul1
Ambrosino, Mario D.1
Atkins, Virginia Foster1
Dempsey, Stephen D.1
more Creators »

Date

Date range begin – Date range end

Current results range from 1981 to 2017

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Decade

2010-20194
2000-20091
1990-199914
1980-198913

Degree Field

Education12
Pharmacy8
Human Performance7
Applied Economics2
Crop and Soil Science1
more Degree Fields »

Degree Level

Doctoral32

Degree Name

Doctor of Philosophy (Ph.D.)[remove]32

Language

English [eng]32

License

All rights reserved5

Non-Academic Affiliation

Oregon State University. Graduate School[remove]32

Peer Reviewed

No32

Resource Type

Dissertation32

Rights Statement

Copyright Not Evaluated25
In Copyright7

Subject

Motor ability in children4
Motor learning4
Mentally handicapped -- Education2
Oral vaccines2
Physical education for handicapped persons2
more Subjects »

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