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Filtering by: Creator Cross, Tim Degree Name Doctor of Philosophy (Ph.D.) Subject Bacteriophage T4

Bacteriophage T4 ribonucleotide reductase : genes and proteins

Creator:

Hanson, Eric Scott

Resource Type:

Dissertation

Full Text:

without dATP 119 4.9. Cross linking of R2 and a 43-kDa protein using DTSSB 121 4.10. R1/R2 synthesis and
Enzyme associations in deoxyribonucleotide biosynthesis : anti-idiotypic antibodies as probes for direct protein-protein interactions

Creator:

Young, James Patrick

Abstract:

The ability to faithfully replicate DNA is dependent upon the maintenance and regulation of its precursors, the deoxyribonucleoside triphosphates. Enzymes encoded by the bacteriophage T4 have been widely used as models of biochemical processes. A body of evidence supports the concept that the bacteriophage T4 enzymes involved in deoxyribonucleotide biosynthesis...

Resource Type:

Dissertation

Full Text:

paths cross again. I would like to thank my parents, Jim and Cheryl Young for their faith and support
Deoxyribonucleotides as determinants of DNA replication fidelity in bacteriophage T4

Creator:

Sargent, Roy Geoffrey

Abstract:

Imbalanced deoxyribonucleoside triphosphate (dNTP) pools are mutagenic for DNA synthesis in both intact cells and cell-free replication systems. Almost certainly, such mutagenesis involves competition between correctly and incorrectly base-paired precursors at replication sites. However, there are certain differences between the intact cell and cell-free systems that do not always allow...

Resource Type:

Dissertation
Host kinases involved in DNA precursor biosynthesis during bacteriophage T4 infection

Creator:

Bernard, Mark Aguirre

Abstract:

Although the Escherichia coli host has almost all of the enzymes necessary to synthesize nucleotides needed for bacteriophage T4 DNA replication, phage genes expressed early in infection encode enzymes for de novo DNA precursor biosynthesis and salvage from degraded host DNA. Eight early enzymes and two host enzymes comprise the...

Resource Type:

Dissertation