Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder experienced by 10–15% of the global population, manifesting as chronic abdominal pain, bloating and inconsistent bowel habits. The search for effective treatments remains ongoing. One promising contender in this realm is kappa-casein glycomacropeptide (GMP), a milk-derived peptide. Its potential benefits stem...
Aromatic hydrocarbons represent a large class of environmental contaminants that have a broad range of structures, physicochemical properties, and toxicities. Arising from the burning of organic matter, particularly fossil fuels, they are both widespread and abundant in all environmental compartments. Both monoaromatic hydrocarbons (BTEX) and polycyclic aromatic hydrocarbons (PAHs) are...
Learning to recognize objects is a fundamental and essential step in human perception and understanding of the world. Accordingly, research of object discovery across diverse modalities plays a pivotal role in the context of computer vision. This field not only contributes significantly to enhancing our understanding of visual information but...
Rapid and sensitive detection of stress hormones, such as cortisol and dehydroepiandrosterone (DHEA), can benefit the diagnosis of diseases related to adrenal gland disorders, post-traumatic stress disorders, chronic fatigue syndrome, and more. Stress hormones fluctuate in a circadian rhythm, the highest in the early morning and the lowest at night;...
Professional school counselors are tasked with providing effective and relevant career counseling and career-focused activities with all K–12 students; however, the career domain remains the area where school counselors feel least efficacious and competent to broach as part of their role. Addressing the career domain in schools is vital as...
Metabolomics has recently gained momentum in biomolecule research and complements the genomics and proteomics research space. Metabolomics strives to detect, identify, and quantify all metabolites present in biological samples. In particular, biomolecular analysis using ultra-performance liquid chromatography combined with mass spectrometry (UPLC-MS) has become increasingly important for metabolomic analyses. Similarly,...
In the most challenging nuclear power plant accidents, transient critical heat flux (CHF) is a primary phenomenon that drives peak cladding temperature and ultimately fuel failure. It is not yet determined whether the use of steady-state CHF methods can accurately predict transient CHF under the conditions of a blowdown due...
Among the candidates for the next generation of nuclear power plant is the high temperature gas reactor (HTGR). Since the HTGR does not have the same operational history as water cooled reactors do in the United States, investigation into the response of different accident phenomena is still an active area...
This work investigates the acoustic velocity of gas-liquid mixtures in vertical, co-current flow in a concentric annulus. Acoustic velocity shows promise as a detection parameter for the presence and amount of gas in a liquid flow because of its high sensitivity to gas void fraction in a gas-liquid mixture. However,...