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Filtering by: Subject Anticonvulsants Degree Name Doctor of Philosophy (Ph.D.)

Activation of adenosine receptors in prepiriform cortex modulates seizure susceptibility

Creator:

Zhang, Ge, 1956-

Resource Type:

Dissertation

Full Text:

study was to characterize the anticonvulsant actions mediated by activation of the adenosine receptor
Adenosine receptor modulation of seizure susceptibility in rats

Creator:

Szot, Patricia

Abstract:

Adenosine is considered to be a neuromodulator or cotransmitter in the periphery and CNS. This neuromodulatory action of adenosine may be observed as an anticonvulsant effect. Dose-response curves for R-phenylisopropyladenosine (PIA), cyclohexyladenosine (CHA), 2-chloroadenosine (2-ClAdo), Nethylcarboxamidoadenosine (NECA) and S-PIA were generated against PTZ seizure thresholds in the rat. The rank...

Resource Type:

Dissertation

Full Text:

observed as an anticonvulsant effect. Dose-response curves for R-phenylisopropyladenosine (PIA
Advanced studies on cyclic amino acids in neurological signaling and peptide antibiotics

Creator:

Blanchard, David, L.

Abstract:

L-pipecolic acid (L-PA) is the higher homolog of proline. It occurs naturally in many organisms, including primates, as an intermediate in lysine degradation. The pathway by which lysine is converted into L-pipecolic acid employs the enzyme Lpipecolate oxidase (L-PO), and appears to be tissue specific to the central nervous system...

Resource Type:

Dissertation