Index Catalog // ScholarsArchive@OSU

Advanced Mass Spectrometry Techniques for Characterizations of Proteome and Lipidome Profiles of Osteosarcoma Cells

Creator:: Song, Zifeng
Abstract:: Mass Spectrometry has emerged as an analytical core technique in omics sciences, in particularly mass spectrometry has advanced the fields of proteomics, metabolomics and lipidomics in recent years. Mass spectrometric techniques have enabled the characterization and determination of abundance levels of a wide range of biomolecules at molecular and system-wide...
Resource Type:: Dissertation
Full Text:: Miranda for his assistance in cell cultures and biochemistry assays. I would like to thank Dr. Liping

Interaction of recombinant factor VIII and the nonionic surfactant Tween 80 at interfaces

Creator:: Joshi, Omkar
Abstract:: The role of the nonionic surfactant Tween 80 on the behavior of the therapeutic recombinant protein Factor VIII (rFVIII) was investigated at solid/liquid and air/water interfaces. In order to provide a model system to compare results obtained for the complicated rFVIII-Tween system, a well-characterized globular protein lysozyme was used. The...
Resource Type:: Dissertation
Full Text:: , Bapu: thanks for everything. CONTRIBUTION OF AUTHORS Liping Chu performed the surface tension

Precursor Chemistry and Film Structure and Properties via Solution Deposition

Creator:: Huang, Yu
Abstract:: Chemistry of preparing dense film from solution deposition is explored with several cases in this thesis. Surface dense structure, conversion at melting point, and ion exchange in aqueous solution are the main topics covered here for the thin films of aluminum oxide phosphate and tin dioxide. Thin film density, optical...
Resource Type:: Dissertation

The effect of dietary compounds on human cathelicidin antimicrobial peptide gene expression mediated through farnesoid X receptor and its potential role in gastrointestinal health

Creator:: Campbell, Yan
Abstract:: The human cathelicidin antimicrobial peptide (CAMP) is a broad spectrum microbicidal agent and modulator of both the innate and adaptive immune system. It is induced by 1,25-dihydroxyvitamin D (1,25(OH)₂D₃) through activation of the vitamin D receptor (VDR) and primary bile salts through activation of the xenobiotic nuclear receptor farnesoid X...
Resource Type:: Dissertation
Full Text:: Campbell, Liping Yang, Jun Tu Zhen, Brian Sinnott, Mary L. Fantacone, Jan F. Stevens, Claudia Maier and

Identifying Differences in the Release of Bioactive Milk Peptides Across the Intestinal Tract Between Term and Preterm Infants

Creator:: Beverly, Robert L.
Abstract:: Premature birth interrupts the typical development of the human fetus, leaving the infant born with underdeveloped gastrointestinal and immune systems. Preterm infants have reduced stomach acidity, reduced digestive protease activity, more permeable intestinal membranes, impaired innate and adaptive immune response, and poor microbiome development. Due to these factors, preterm infants...
Resource Type:: Dissertation
Full Text:: –and Liping Yang and Stanislau Stanisheuski at the Mass Spectrometry Center. Their mentorship in

Test Case Reduction, Prioritization, and Selection for Symbolic Execution

Creator:: Zhang, Chaoqiang
Abstract:: Software testing is of critical importance for the success of software projects. Current inefficient testing methods often still take up half or more of a software project's budget. Automatic test data generation is the most promising way to lower the software testing cost. Manually creating testing data is expensive and...
Resource Type:: Dissertation
Full Text:: , Piawah Sim, Kok Meng Lam, Craig Hanson, Liping Hu, Sherman Juang, Catherine Fang, and Gary Ferngren for

Multi-instance multi-label learning : algorithms and applications to bird bioacoustics

Creator:: Briggs, Forrest
Abstract:: We consider the problem of supervised classification of bird species from audio recordings in a real-world acoustic monitoring scenario (i.e. audio data is collected in the field with an omnidirectional microphone, without human supervision). Obtaining better data about bird activity can assist conservation efforts, and improve our understanding of their...
Resource Type:: Dissertation

Comprehensive Analysis of The Brain Metabolome Using Mass Spectrometry in Conjunction with Data Analysis Techniques

Creator:: Khorani, Mona
Abstract:: Metabolomics has recently gained momentum in biomolecule research and complements the genomics and proteomics research space. Metabolomics strives to detect, identify, and quantify all metabolites present in biological samples. In particular, biomolecular analysis using ultra-performance liquid chromatography combined with mass spectrometry (UPLC-MS) has become increasingly important for metabolomic analyses. Similarly,...
Resource Type:: Dissertation
Full Text:: . Furthermore, I am grateful to Jeffrey Morre and Dr. Liping Yang for their invaluable assistance with mass

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Creator:: Padgitt-Cobb, Lillian K.
Abstract:: Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
Resource Type:: Dissertation

Harnessing Heterogeneity in Human Gut Microbiome Data

Creator:: Tataru, Christine
Abstract:: The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
Resource Type:: Dissertation

ScholarsArchive@OSU

Advanced Mass Spectrometry Techniques for Characterizations of Proteome and Lipidome Profiles of Osteosarcoma Cells

Interaction of recombinant factor VIII and the nonionic surfactant Tween 80 at interfaces

Precursor Chemistry and Film Structure and Properties via Solution Deposition

The effect of dietary compounds on human cathelicidin antimicrobial peptide gene expression mediated through farnesoid X receptor and its potential role in gastrointestinal health

Identifying Differences in the Release of Bioactive Milk Peptides Across the Intestinal Tract Between Term and Preterm Infants

Test Case Reduction, Prioritization, and Selection for Symbolic Execution

Multi-instance multi-label learning : algorithms and applications to bird bioacoustics

Comprehensive Analysis of The Brain Metabolome Using Mass Spectrometry in Conjunction with Data Analysis Techniques

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Harnessing Heterogeneity in Human Gut Microbiome Data

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