Index Catalog // ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Creator:: Maxwell, Joseph R.
Abstract:: T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
Resource Type:: Dissertation
Full Text:: Costimulation and Adjuvants in the Development of T Cell Effector and Memory Responses. Abstract approved

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

Creator:: Shepherd, David M.
Abstract:: The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
Resource Type:: Dissertation
Full Text:: -Tetrachlorodibenzo-p-dioxin on T Cell Activation by David M. Shepherd A DISSERTATION submitted to

An Investigation into the Functional Properties of the Deafness Causing Protein Otoferlin

Creator:: Manchanda, Aayushi
Abstract:: Otoferlin is a C2-domain, transmembrane protein whose mutated form is responsible for the DFNB9 subtype of prelingual hearing impairment. Mutations in otoferlin cause an autosomal recessive, non-syndromic form of deafness that is characterized by auditory neuropathy/ auditory dissynchrony (AN/AD), meaning that the outer hair cells (OHCs) are normal, and the...
Resource Type:: Dissertation
Full Text:: . Johnson Abstract Otoferlin is a C2-domain, transmembrane protein whose mutated form is

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

Creator:: Prell, Rodney A.
Resource Type:: Dissertation
Full Text:: of 2,3,7,8-tetrachlorodibenzo-p- dioxin-Induced Immunotoxicity in C57B1/6 Mice: Effects on T Cell

The influence of aryl hydrocarbon receptor activation on T cell fate

Creator:: Funatake, Castle J.
Abstract:: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
Resource Type:: Dissertation
Full Text:: Hydrocarbon Receptor Activation on T Cell Fate. approved: 2,3,7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) and

T lymphocyte death as a potential mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immune suppression

Creator:: Dearstyne, Erica A.
Resource Type:: Dissertation
Full Text:: -tetrachlorodibenzo-p-dioxin (TCDD or dioxin). T lymphocyte- dependent responses are particularly sensitive to the

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B(SEB)-induced alterations in T-cell activation and cytokine production

Creator:: Huang, Wentian
Resource Type:: Dissertation
Full Text:: -Tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B (SEB)-Induced Alterations in T-Cell Activation

The decay of Pd¹⁰⁹, Pd¹¹¹ [superscript g], and Pd¹¹¹ [superscript m]

Creator:: Barnes, W. Earl
Abstract:: The decay of Pd¹⁰⁹, Pd¹¹¹ [superscript g], and Pd¹¹¹ [superscript m] produced by thermal neutron irradiation of palladium targets has been investigated. Gamma ray energies and relative intensities have been measured with a high resolution Ge(Li) spectrometer. From energy sums and relative intensity considerations level schemes for Ag ¹⁰⁹ and...
Resource Type:: Dissertation
Full Text:: . Lo .1oO co En In VC co .44 .4. .Ni. ,:t. .., N.0 m 412(5/ . 307(3/ ; Z S b, .. _______

Exchange reactions in liquid sulfur dioxide

Creator:: Johnson, Rowland Edward
Resource Type:: Dissertation
Full Text:: the m.os t general or these .is the Lewis Theot-y (14, p.l6) which states that an acid is a aubstanee

Physical and chemical properties of ribonuclease T₁

Creator:: Miller, Terry L.
Abstract:: The spectrophotometric titration of the tyrosine residues, their reaction with N-acetylimidazole, and the effect of pH on the thermally induced conformational transition of ribonuclease T₁ have been investigated. The results of spectrophotometric titration in 0.20 M KCl/0.001 M sodium phosphate suggest that titration of the tyrosine residues occurs in two...
Resource Type:: Dissertation
Full Text:: dissolved in 0.9 ml of 0.025 M Veronal, pH 7.5, and then 0.1 ml of RNase T 1 solu- tion (10 mg/m1) was

ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

An Investigation into the Functional Properties of the Deafness Causing Protein Otoferlin

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

The influence of aryl hydrocarbon receptor activation on T cell fate

T lymphocyte death as a potential mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immune suppression

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B(SEB)-induced alterations in T-cell activation and cytokine production

The decay of Pd¹⁰⁹, Pd¹¹¹ [superscript g], and Pd¹¹¹ [superscript m]

Exchange reactions in liquid sulfur dioxide

Physical and chemical properties of ribonuclease T₁

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