Index Catalog // ScholarsArchive@OSU

Functional transition metal oxides : structure-property relationships

Creator:: Smith, Andrew E.
Abstract:: Transition metal oxides are an important class of materials for the wide variety optical, electrical, dielectric, magnetic, and thermal properties observed. Their unique structure-property relationships allow for property tuning and often provide insight into the fundamentals of chemistry. The work in this thesis was focused on the design, synthesis and...
Resource Type:: Dissertation
Full Text:: formula such as YAl1-xMnxO3-y(CO3)y. For the high-k dielectric CaCu3-xMnxTi4-yFeyO12 and CaCu3Ti4O12

Development of 2D models to estimate nearshore bathymetry and sediment transport

Creator:: Splinter, Kristen D.
Abstract:: We examine the interactions and feedbacks between bathymetry, waves, currents, and sediment transport. The ﬁrst two pro jects focus on the use of remote sensing techniques to expand our knowledge of the nearshore. Due to the plethora of snap-shot data that is available from satellites and their distribution via Google...
Resource Type:: Dissertation
Full Text:: -shore, ∂Qx/∂x, and the alongshore, ∂Qy/∂y, directions. The problem is under-determined, having two

Evidence for the involvement of a mitochondrial permeability transistion in a victorin-Induced cell death

Creator:: Curtis, Marc James
Abstract:: Production of the host selective toxin victorin is causal to pathogenesis of Cochliobolus victoriae on oats. The dominant Vb gene confers oat sensitivity to victorin, and is genetically inseparable from Pc2, which confers resistance to Puccinia coronata f. sp. avena. Victorin induces apoptotic-like cell death, and cell death is a...
Resource Type:: Dissertation
Full Text:: PCD (Kuriyama and Fukuda, 2002). Differentiation of tracheaiy elements (TEs) into empty cell corpses

The effects of the carcinostatic compound 1, 3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on the hepatic microsomal enzyme systems in rats

Creator:: Lu, Irene
Abstract:: Preliminary toxicity studies of BCNU in rats revealed that significant prolongations of pentobarbital hypnosis were associated with all doses employed. Investigations were undertaken to determine the underlying mechanism responsible for this observed effect. Studies on the in vitro metabolism of pentobarbital by hepatic microsomes of BCNU-treated animals demonstrated that significant...
Resource Type:: Dissertation
Full Text:: of the two hemoproteins, cytochrome P-450 (Omura and Kuriyama, 1969). Indeed, it was shown that in

Utilization of the Zebrafish Model for Investigating Nitrated Polycyclic Aromatic Hydrocarbon Developmental Toxicity

Creator:: Chlebowski, Anna C.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are among the most widely known and studied environmental contaminants, originating from a range of natural and anthropogenic sources. PAHs are known to occur in the environment as complex mixtures, containing both unsubstituted PAHs, as well as a range of PAH derivatives. Among the less-studied of...
Resource Type:: Dissertation
Full Text:: ; 12 Ramesh et al., 2004; Shimada and Fujii-Kuriyama, 2004). These DNA adducts, if not repaired

Ligand selective regulation of cell growth by the Ah receptor through activation of TGF-beta signaling, Ligand selective regulation of cell growth by the Ah receptor through activation of TGFβ signaling

Creator:: Koch, Daniel C.
Abstract:: The Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and member of the basic helix-loop-helix Per/ARNT/Sim (bHLH/PAS) family of chemosensors and developmental regulators. As a member of the PAS domain family of transcription factors responsive to exogenous signals, the AhR exerts influence on many processes relating to cellular fate....
Resource Type:: Dissertation
Full Text:: between the models (Lahvis and Bradfield 1998, Esser 2009). The Fujii- Kuriyama group generated AhR

Critical windows of transplacental carcinogenesis : identifying efficacious approaches to chemoprevention with dietary phytochemicals

Creator:: Castro, David J.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are a re-emerging class of environmental pollutants. The persistent nature of these highly toxic compounds along with their ubiquity in the environment creates an unavoidable route of exposure. The developing fetus and neonate are a particularly susceptible population due to their incomplete complement of xenobiotic metabolizing...
Resource Type:: Dissertation
Full Text:: systems upon metabolic activation to chemically reactive species (Shimada and Fujii-Kuriyama, 2004

Adapting computer science technologies to bridge critical gaps in proposed Tox21 risk assessment programs

Creator:: Larkin, Andrew
Abstract:: In 2004 the National Toxicology Program published an article describing their intent to pursue toxicology testing and risk assessment practices solely reliant on high throughput in vitro datasets and in silico modeling for dose-response assessments. Support and contributions form regulatory agencies and a significant portion of the life sciences community...
Resource Type:: Dissertation
Full Text:: hydrocarbon receptor (AhR) activation (Fujii-Kuriyama and Mimura, 2005; Lin et al., 2003). The AhR pathway

Characterization of pyruvate carboxylase responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure in C57BL/6J male Ah[superscript d/d] mice

Creator:: Ryu, Byung-Woo
Resource Type:: Dissertation
Full Text:: lethality. Biochem. Biophy. Res. Comm. 174: 1267 1271. Mackay, D., Shiu, W.-Y., and Ma, K (1992

Investigations of the AhR-induced Treg : transcriptional regulation and suppressive mechanisms

Creator:: Rohlman, Diana
Abstract:: The aryl hydrocarbon receptor (AhR) has recently been described as a novel therapeutic target, given the potent suppression of multiple immune-mediated diseases following activation by the prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In the parent-into-F1 graft-versus-host (GVH) model, suppression of the cytotoxic T-lymphocyte (CTL) response is associated with the presence of CD25⁺CTLA-4⁺IL-10⁺Foxp3[superscript...
Resource Type:: Dissertation

ScholarsArchive@OSU

Functional transition metal oxides : structure-property relationships

Development of 2D models to estimate nearshore bathymetry and sediment transport

Evidence for the involvement of a mitochondrial permeability transistion in a victorin-Induced cell death

The effects of the carcinostatic compound 1, 3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on the hepatic microsomal enzyme systems in rats

Utilization of the Zebrafish Model for Investigating Nitrated Polycyclic Aromatic Hydrocarbon Developmental Toxicity

Ligand selective regulation of cell growth by the Ah receptor through activation of TGF-beta signaling, Ligand selective regulation of cell growth by the Ah receptor through activation of TGFβ signaling

Critical windows of transplacental carcinogenesis : identifying efficacious approaches to chemoprevention with dietary phytochemicals

Adapting computer science technologies to bridge critical gaps in proposed Tox21 risk assessment programs

Characterization of pyruvate carboxylase responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure in C57BL/6J male Ah[superscript d/d] mice

Investigations of the AhR-induced Treg : transcriptional regulation and suppressive mechanisms

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