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Filtering by: Creator Roché, Cindy Talbott Remove constraint Creator: Roché, Cindy Talbott Degree Name Doctor of Philosophy (Ph.D.) Remove constraint Degree Name: Doctor of Philosophy (Ph.D.)

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  • Mechanisms of Vigilance Loss in Sensory and Cognitive Tasks

    Creator:
    Gyles, Shannon P.
    Abstract:
    When observers monitor for infrequent signals for extended durations, they generally experience a decline in detections over time. This decline is termed the vigilance decrement. Current theories of vigilance attribute the decrement to three potential mechanisms: conservative shifts in response bias, losses of sensitivity, and an increased rate of attentional...
    Resource Type:
    Dissertation

  • Functional Materials and Techniques for Additive Manufacturing in Soft Robotics

    Creator:
    Walker, Stephanie
    Abstract:
    This thesis outlines the development of new elastomeric materials and manufacturing processes for soft robotics. Specifically, this work describes the development of custom material formulations for use in additive manufacturing, additive manufacturing processing techniques for silicone elastomers, and multi-component additive manufacturing techniques. Material synthesis and processing is a gap in...
    Resource Type:
    Dissertation
    Full Text:
    experiments Samantha Hemleben – performed motion capture experiment Cindy Grimm – provided text for motion

  • Protein Disorder in the Evolution of Dynein Regulation

    Creator:
    Jie, Jing
    Abstract:
    Intrinsically disordered proteins (IDP) are a class of proteins that lack a three-dimensional structure and their prevalence and diverse functions in the cell have only been discovered relatively recently. The intermediate chain (IC) subunit of the microtubule motor protein complex dynein contains an N-terminal disordered region, N-IC, which is central...
    Resource Type:
    Dissertation

  • Frost hardiness of buds, flowers and fruit of pear (Pyrus communis L.)

    Creator:
    Strang, John George
    Abstract:
    Spring frost damage to pears in the Pacific Northwest frequently results in substantial crop losses. This research was undertaken to investigate the effects of frost on pear buds, flowers, and fruit through controlled freezing tests and field studies in order to better understand the frost phenomenon and refine frost protection...
    Resource Type:
    Dissertation
    Full Text:
    treatment of this data. Special thanks are extended to Frank Papen, Cindy Hunt, Keith Graves, Sidney

  • Human exposure to polycyclic aromatic hydrocarbons : global cancer risk and metabolism

    Creator:
    Motorykin, Oleksii
    Abstract:
    In recent decades, there has been increased attention on human exposure to, and subsequently toxicity of, Polycyclic Aromatic Hydrocarbons (PAHs). PAHs are widespread organic pollutants and some have been shown to be toxic, carcinogenic and mutagenic. This research was focused on understanding the link between global PAH emissions and lung...
    Resource Type:
    Dissertation

  • What is killing the corals? Viral and bacterial interrogations using metagenomics and microscopy

    Creator:
    Soffer, Nitzan
    Abstract:
    Corals have multiple roles in maintaining ocean health and are some of the world’s most diverse ecosystems. The coral animal is host to a multitude of taxa, including symbiotic dinoflagellate algae, fungi, bacteria, protists, and viruses. Environmental stressors and disease agents can perturb the delicate balance of the coral host...
    Resource Type:
    Dissertation
    Full Text:
    of course my friends from Florida, Zack, Cindy, Robin, Xaymara, Maria, Kristen, and Laura, even

  • Evolutionary Dynamics of Genomes and Endosymbionts in Plant-Parasitic Nematodes

    Creator:
    Wasala, Wasala Mudiyanselage Sulochana K.
    Abstract:
    Plant-parasitic nematodes cause more than US $100 billion in annual agriculture loss worldwide. Thorough knowledge of their genetic diversity, and interactions with endosymbionts and environment have the potential to provide valuable insights into the basic biology of these animals, and assist future efforts aimed at management of these plant parasites....
    Resource Type:
    Dissertation
    Full Text:
    , as compared to Sanger sequencing (Schuster, 2008). The NGS technologies include: (i) Roche 454, (ii

  • Biophysical basis of macromolecular assembly in the dynein cargo attachment complex

    Creator:
    Hall, Justin Daniel
    Abstract:
    Cytoplasmic dynein is an ATP-dependent, microtubule-based molecular motor involved in the positioning and trafficking of cellular cargo. The cargo binding sub-domain of dynein contains the natively disordered intermediate chain (IC) and the homodimeric light chains (Tctex1, LC8 and LC7). The structure and stoichiometry of this complex, how the light chains...
    Resource Type:
    Dissertation
    Full Text:
    and 89 a.a. in D. melanogaster, respectively) homodimeric proteins (Barbar et al. 2001; Talbott et

  • Functional and Structural Analyses of Three Distinct proteins by Biochemical and Biophysical Techniques

    Creator:
    Codding, Sara Jone
    Abstract:
    The focus of this dissertation was to understand protein function and structure ona molecular level. To do this successfully, a variety of biochemical and biophysicaltechniques were employed. A wide variety of techniques were applied to study theproteins of interest in this dissertation to probe protein-protein interactions, proteinfunction, protein structure, and...
    Resource Type:
    Dissertation
    Full Text:
    research, their foundation of support has never wavered. My parents, Jim and Cindy who both feed my

  • Investigating Multimodal Therapies with Nanotechnology to Engineer Advanced Chemoradiation Platforms

    Creator:
    DuRoss, Allison N.
    Abstract:
    The potential for nanomedicine to reduce toxicity and improve therapeutic response to radiation is vast. Clinically, this potential has thus far only begun to be realized with the recent success of the radioenhancing nanoparticle, NBTXR3 by Nanobiotix. Radioenhancing nanoparticles, however, represent only a small class of nanomaterials that may be...
    Resource Type:
    Dissertation
    Full Text:
    . To my in-laws, Mike and Cindy, thank you for sharing your son and being supportive of our journey