Index Catalog // ScholarsArchive@OSU

Expression and G protein coupling of the M2 muscarinic acetylcholine receptor in Sf9 insect cells

Creator:: Mosser, Valerie A.
Resource Type:: Dissertation
Full Text:: independent pathways requires protein kinase C and involves the smaH G protein raf in the activation of ERK

Ascorbylation- the biological relevance of covalently bound ascorbic acid

Creator:: Kesinger, Nicholas G.
Abstract:: Ascorbic acid, or vitamin C, is well known as a co-factor for proline-hydroxylase and as an anti-oxidant. However, it is also capable of forming covalent bonds, particularly in the role of a nucleophile, henceforth termed 'ascorbylation'. The ascorbylation of electrophiles can occur under physiological conditions. Furthermore, there are a number...
Resource Type:: Dissertation
Full Text:: Nicholas G. Kesinger for the degree of Doctor of Philosophy in Pharmacy presented on September 8th, 2009

G, a language based on demand-driven stream evaluations

Creator:: Placer, John R.
Abstract:: A programming paradigm can be defined as a model or an approach employed in solving a problem. The results of the research described in this document demonstrate that it is possible to unite several different programming paradigms into a single linguistic framework. The imperative, procedural, applicative, lambda-free, relational, logic and...
Resource Type:: Dissertation
Full Text:: for G. This goal was also realized. The G interpreter consists of approximately 5000 lines of C code

The ascorbic acid requirements of older adolescents

Creator:: Davey, Bessie Louise
Abstract:: The concentration of ascorbic acid in the plasma was determined on four levels of ascorbic acid intake for seven day periods in 1946-47 and on three levels of ascorbic acid intake for ten day periods in 1947-48. The subjects, eight girls and eight boys, were 16 to 19 year old...
Resource Type:: Dissertation
Full Text:: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60 C. Total Daily Intake of Ascorbic Acid and Daily Plasma Ascorbic Acid Values for Adolescent Boys

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Creator:: Zhang, Yong
Abstract:: Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Prior research suggested that some isoforms of PLC-β may exist and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation assays of differentially-tagged PLC-β constructs and sizeexclusion chromatography of native PLC-β support homodimerization...
Resource Type:: Dissertation
Full Text:: activity but completely abrogated Gαq-stimulated activity in vitro, indicating the C-tail is important

Regulation of phospholipase C-beta isozymes by calmodulin

Creator:: McCullar, Jennifer Star
Abstract:: Phospholipase C-Jβ (PLCβ) is an important effector enzyme in G-protein-coupled signaling pathways. Activation of PLCβ by Gα and Gβy subunits has been fairly well characterized, but little is known about other protein interactions that may also regulate PLCβ function. A yeast two-hybrid screen of a mouse brain cDNA library with...
Resource Type:: Dissertation
Full Text:: Phospholipase C-J3 (PLC3) is an important effector enzyme in G-protein-coupled signaling pathways. Activation

Part I: Synthetic Studies toward C10-functionalized Lycopodium Alkaloids. Part II: Exploration of the Pummerer Cyclization and Its Application to the Total Syntheses of the Abietane Diterpenoids

Creator:: Li, Xin
Abstract:: This dissertation is separated into two parts according to the two major distinct research projects. In Part I, the full account of synthetic studies toward C10-functionalized lycopodium alkaloids is described. In Part II, the detailed discussion on the exploration of the Pummerer cyclization methodology and its application to the total...
Resource Type:: Dissertation
Full Text:: : ______________________________________________________ Rich G. Carter This dissertation is separated into two parts according to the two major

Hydrogen isotopic composition of C₃₇ alkenones and the ecology and physiology of coccolithophores

Creator:: Wolhowe, Matthew D.
Abstract:: A three-part study was conducted into the impact of physiological and ecological variables on the net isotopic fractionation of hydrogen, α[subscript K₃₇], expressed in C₃₇ alkenones. First, alkenone-producer production, abundance, and export were characterized in the summertime Gulf of California and Eastern Tropical North Pacific using compound-specific, labeled in situ...
Resource Type:: Dissertation
Full Text:: Fredrick G. Prahl A three-part study was conducted into the impact of physiological and ecological

A unified approach for the total synthesis of C₁₀-functionalyzed Lycopodium alkaloids

Creator:: Saha, Mrinmoy
Abstract:: Lycopodium alkaloids have shown widespread and noteworthy biological activity, consisting of over 250 known natural products. Moreover, their structural complexity and diversity have attracted considerable attention from numerous laboratories including our own. Recently, we have developed a unified approach that would provides access to numerous, previously unprepared C₁₀-functionalized lycopodium alkaloids....
Resource Type:: Dissertation
Full Text:: NaBH4 provided (-)-cermizine C 1.15. Scheme 1.18: Snider’s Syntheses of (-)-Senepodine G

Inhibition of exercise-induced oxidative stress, inflammation and muscle damage by prior supplementation with the antioxidant vitamins E and C

Creator:: Mastaloudis, Angela
Abstract:: To determine if 6 weeks prior supplementation with vitamins E and C could alleviate exercise-induced DNA damage, prevent lipid peroxidation and inflammation, slow the rate of vitamin E utilization and/or attenuate muscle damage, 22 subjects (11 females: 11 males) were studied during a 50 km (32 mile) ultramarathon. Subjects were...
Resource Type:: Dissertation
Full Text:: the Antioxidant Vitamins E and C. Abstract approved: Maret G. Traber To determine if 6 weeks prior

ScholarsArchive@OSU

Expression and G protein coupling of the M2 muscarinic acetylcholine receptor in Sf9 insect cells

Ascorbylation- the biological relevance of covalently bound ascorbic acid

G, a language based on demand-driven stream evaluations

The ascorbic acid requirements of older adolescents

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Regulation of phospholipase C-beta isozymes by calmodulin

Part I: Synthetic Studies toward C10-functionalized Lycopodium Alkaloids. Part II: Exploration of the Pummerer Cyclization and Its Application to the Total Syntheses of the Abietane Diterpenoids

Hydrogen isotopic composition of C₃₇ alkenones and the ecology and physiology of coccolithophores

A unified approach for the total synthesis of C₁₀-functionalyzed Lycopodium alkaloids

Inhibition of exercise-induced oxidative stress, inflammation and muscle damage by prior supplementation with the antioxidant vitamins E and C

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