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Filtering by: Creator Sepúlveda, J. Remove constraint Creator: Sepúlveda, J. Degree Name Honors Bachelor of Science (H.B.S.) Remove constraint Degree Name: Honors Bachelor of Science (H.B.S.) License All rights reserved Remove constraint License: All rights reserved

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  • Investigating the Role of the MutLα Endonuclease

    Creator:
    Mankaney, Gautam Naresh
    Abstract:
    Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
    Resource Type:
    Honors College Thesis