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Filtering by: Creator Filichkin, Sergei A. Degree Name Honors Bachelor of Science (H.B.S.)

Validation of Predicted Functional Transcription Factor Binding Sites in Arabidopsis thaliana

Creator:

Ozguc, Olivia R.

Abstract:

Gene expression is largely regulated by the binding of transcription factors to short sequences of DNA (transcription factor binding sites) to drive or repress transcription of an adjacent gene. Identifying the key transcription factor binding sites associated with a particular biological outcome provides an avenue for tailored transcriptional regulation in...

Resource Type:

Honors College Thesis

Full Text:

was built using data generated by Maria Ivanchenko and Sergei Filichkin, with algorithms implemented
Effects of Oxidative Stress on Circadian Gene Expression during Aging

Creator:

Bonar, Tara

Abstract:

All organisms possess circadian clocks, which generate daily oscillations in clock controlled gene expression that regulate many essential biological functions in synchrony with the 24-hour light/dark cycles. When the genes that control the internal clock are weakened, accelerated aging symptoms are observed. Past research in Drosophila demonstrated that aging flies...

Resource Type:

Honors College Thesis

Full Text:

Computer Science Sergei Filichkin, Committee Member, representing Department of Botany and Plant
Exploring Links between Circadian Rhythms and Healthy Aging

Creator:

Mattison, Braden J.

Abstract:

Circadian rhythms are the daily oscillations in multiple organism functions, from clock gene expression to behavior. Lost or irregular rhythms lead to health problems later in life including nervous system disorders, abnormal sleep/activity cycles, diabetes and obesity. However, it is not known whether strengthening the expression of clock genes throughout...

Resource Type:

Honors College Thesis

Full Text:

Member, representing Integrative Biology Sergei Filichkin, Committee Member, representing Botany and