Index Catalog // ScholarsArchive@OSU

Evaluation of Oxidation Reduction Potential in Metabolic Syndrome Subjects Compared with Matched Normal Subjects

Creator:: Cobb, Tora Jean
Abstract:: This study was conducted to assess whether healthy adults compared with those with Metabolic Syndrome (MetS) have different mean oxidative-reductive potentials. Static oxidation-reduction potentials and capacity oxidation reduction potentials (sORP and cORP, respectively) were measured in plasma samples. The RedoxSYS® measures sORP in millivolts (mV), which is proportional to the...
Resource Type:: Honors College Thesis
Full Text:: . Abstract approved: ______________________________________________________ Maret G. Traber

Impact of Vitamin E Deficiency on Hepatic Gene Expression of CRAL_TRIO Family Proteins in a Premier Vertebrate Animal Model

Creator:: Watt, Alexander T.
Abstract:: Vitamin E (vitE) is a group of lipid-soluble antioxidants- of which alpha-tocopherol is the most biologically active and only form considered to be an essential nutrient. Through preferential binding and trafficking, the alpha-tocopherol transfer protein (α-TTP) regulates the concentration of vitE in the body. The impact of vitE deficiency on...
Resource Type:: Honors College Thesis
Full Text:: : _____________________________________________________ Maret G. Traber Vitamin E (vitE) is a group of lipid-soluble antioxidants- of which alpha

Gender-Dependent Mechanisms of Alpha-Tocopherol Protection from Benzo[a]pyrene Exposure in Rats

Creator:: Crimp, Caitlin A.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (B[a]P), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (αT) supplementation decreases B[a]P-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that αT protection from B[a]P exposure is gender-dependent, male and female rats received 7 daily subcutaneous...
Resource Type:: Honors College Thesis
Full Text:: thank Dr. Maret Traber and Dr. Dave Williams for serving as committee members on my honors thesis

The Effect of Protein Nitration on Cell Survival Pathways in Schwann Cells

Creator:: Graumann, Oliver W.
Abstract:: Neurofibromatosis type 2 (NF2) is a genetic disorder caused by the inactivation of the merlin tumor suppressor gene. NF2 patients develop bilateral vestibular schwannomas (VS) and other nervous system tumors with no effective drug treatment option. In pathological conditions, including NF2, production of the oxidant peroxynitrite leads to protein tyrosine...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Maret Traber, Committee Member, representing Biochemistry and Biophysics

Role of Nitrated Hsp90 in Schwannoma Cell Survival

Creator:: Kim, Sharon R.
Abstract:: Neurofibromatosis Type 2 (NF2) is a genetic tumor disorder caused by mutations that inactivate the gene coding for the Merlin tumor suppressor. Patients with NF2 develop multiple tumors throughout the nervous system, mainly schwannomas, for which there is no cure or effective treatment. In NF2, redox signaling and oxidative stress...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Maret G. Traber, Committee Member, representing Public Health and Human Sciences

The Effects of Vitamin E on the Lifespan of Caenorhabditis elegans Strains with Mitochondrial Mutations

Creator:: Kusuma, Danika N.
Abstract:: Although assays have been done on the effects of vitamin E alpha-tocopherol (ɑ-tocopherol) on the lifespan of wildtype C. elegans, none have been done on the effects of the vitamin on mutant strains with mitochondrial mutations. By using a mev-1 genetic mutant strain of C. elegans with higher levels of...
Resource Type:: Honors College Thesis
Full Text:: . 19. Higdon, J., Drake, J., Traber, G. Vitamin E [Internet]. Oregon: Linus Pauling Institute at

Investigating the Interplay of Age, Zinc Status, and the Gut Microbiome on Gut Health

Creator:: Vasudevan, Anusha
Abstract:: Zinc is an important micronutrient involved in many cellular processes, including those part of immune function; however, about 15% of the US population is at risk for marginal zinc deficiency. This can lead to immune system complications including the generation of inflammatory cytokines. Aging is another factor that worsens the...
Resource Type:: Honors College Thesis
Full Text:: . Ecol. Package 2009, 10, 631–637. 25 21. Podda, M.; Weber, C.; Traber, M. G.; Packer, L

The Effect of Zinc Status and Age on Liver Health in Mice

Creator:: Braun, Kendra N.
Abstract:: Age-related diseases have been associated with chronic inflammation and impaired immune response, one of the hallmarks of aging. Aging individuals also have a higher susceptibility to zinc deficiency. The effects of zinc deficiency share many commonalities with the effects of aging on the immune system and zinc deficiency may be...
Resource Type:: Honors College Thesis
Full Text:: , 11(10). https://doi.org/10.3390/nu11102273 Song, Y., Leonard, S. W., Traber, M. G., & Ho, E. (2009

Acupuncture prevents the postpartum reduction in matrix metalloproteinase type-2 concentration and enzyme activity in bovine caruncles

Creator:: Hiebel, Katrina A.
Abstract:: The objectives of this study were to determine the effects of acupuncture in dairy cows on caruncular matrix metalloproteinase type-2 (MMP2) tissue concentration and enzyme activity at 0, 2, and 4 hours after calving. Immediately after natural calving, a caruncle was obtained from the body of the uterus and flash...
Resource Type:: Honors College Thesis
Full Text:: Metalloproteinases. Academic Press, San Diego. Qu, Y., A. N. Fadden, M. G. Traber, and G. Bobe. 2014. Potential

The Effects of In Ovo Feeding of Fatty Acids and Antioxidants on Broiler Chicken Hatchability and Chick Tissue Lipids

Creator:: Schaal, Travis P.
Abstract:: Hatchability of broiler eggs has not increased over the last twenty years. Increasing hatchability with in ovo technology may be possible through feeding metabolic modulators to the developing embryo. Exogenous fatty acids and antioxidants provided during incubation may enhance polyunsaturated fatty acid, lipid, and antioxidant status of the chicken embryo....
Resource Type:: Honors College Thesis
Full Text:: . ____________________________________________________________________________________________________________ 1A version of this chapter has been published previously (Schaal, T., and G. Cherian. 2007

ScholarsArchive@OSU

Evaluation of Oxidation Reduction Potential in Metabolic Syndrome Subjects Compared with Matched Normal Subjects

Impact of Vitamin E Deficiency on Hepatic Gene Expression of CRAL_TRIO Family Proteins in a Premier Vertebrate Animal Model

Gender-Dependent Mechanisms of Alpha-Tocopherol Protection from Benzo[a]pyrene Exposure in Rats

The Effect of Protein Nitration on Cell Survival Pathways in Schwann Cells

Role of Nitrated Hsp90 in Schwannoma Cell Survival

The Effects of Vitamin E on the Lifespan of Caenorhabditis elegans Strains with Mitochondrial Mutations

Investigating the Interplay of Age, Zinc Status, and the Gut Microbiome on Gut Health

The Effect of Zinc Status and Age on Liver Health in Mice

Acupuncture prevents the postpartum reduction in matrix metalloproteinase type-2 concentration and enzyme activity in bovine caruncles

The Effects of In Ovo Feeding of Fatty Acids and Antioxidants on Broiler Chicken Hatchability and Chick Tissue Lipids

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